Findings

What do systematic reviews say?

3,584 questions · 3,695 findings · 567 reviews

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No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Incidence of obstetric complications · pregnant women with gonorrhoea infection

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 168 participants
GRADE not reported

Intramuscular ceftriaxone vs oral cefixime

Incidence of obstetric complications · pregnant women with gonorrhoea infection

1 finding from 1 review

Antibiotics for treating gonorrhoea in pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 95 participants
GRADE not reported

Absorbable vs non‐absorbable sutures

Postoperative pain: early pain (10 days postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)

2 findings from 1 review

Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 137 participants
Very low
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low

Absorbable vs non‐absorbable sutures

Postoperative pain: late pain (6 weeks postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)

1 finding from 1 review

Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 175 participants
Very low

Cannabis‐based medicines vs placebo

Adverse events: psychological disorders · adults with chronic neuropathic pain

1 finding from 1 review

Cannabis‐based medicines for chronic neuropathic pain in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1314 participants
Low

Systemic antifungal vs placebo/no treatment

Generic quality of life measures · chronic rhinosinusitis

The review found no eligible studies for this question.

1 finding from 1 review

Topical and systemic antifungal therapy for chronic rhinosinusitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antifungal vs placebo/no treatment

Generic HRQL (change from baseline) · chronic rhinosinusitis

2 findings from 1 review

Topical and systemic antifungal therapy for chronic rhinosinusitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low
Topical and systemic antifungal therapy for chronic rhinosinusitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Respiratory support vs no respiratory support before cord clamping

Intraventricular haemorrhage · preterm infants

Respiratory support showed no clear difference in intraventricular haemorrhage (of any grade) compared with no respiratory support before cord clamping (low certainty).

1 finding from 1 review

Provision of respiratory support compared to no respiratory support before cord clamping for preterm infants 2018 · Cochrane Headline outcomes only
RR 1.5 [0.65, 3.46]
150 participants
Low

Respiratory support vs no respiratory support before cord clamping

Severe intraventricular haemorrhage · preterm infants

It is very uncertain whether respiratory support changes severe intraventricular haemorrhage grade 3 or 4 compared with no respiratory support before cord clamping (very low certainty).

1 finding from 1 review

Provision of respiratory support compared to no respiratory support before cord clamping for preterm infants 2018 · Cochrane Headline outcomes only
RR 1.33 [0.31, 5.75]
150 participants
Very low

Parent‐mediated communication intervention vs no intervention

Children's generic participation: social · children up to 5 years of age with a communication difficulty associated with any non‐progressive motor disorder acquired before 2 years…

The review found no eligible studies for this question.

1 finding from 1 review

Parent‐mediated communication interventions for improving the communication skills of preschool children with… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention diet vs usual on‐treatment diet

Lactose‐restricted diet · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise vs no exercise

Anthropometric measurements: mid‐arm circumference (cm) · people with Child‐Pugh stage A or B cirrhosis

1 finding from 1 review

Physical exercise for people with cirrhosis 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 72 participants
Low

Exercise vs no exercise

Anthropometric measurements: mid‐thigh circumference (cm) · people with Child‐Pugh stage A or B cirrhosis

1 finding from 1 review

Physical exercise for people with cirrhosis 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 128 participants
Low

4% articaine plain vs 4% articaine, 1:100,000 epinephrine

Duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine plain changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 4% articaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -37.08 [-60.95, -13.21]
2 studies · 100 participants
Very low

2% lidocaine, 1:50,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Speed of onset of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 2% lidocaine, 1:50,000 epinephrine changes speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD -0.44 [-1.66, 0.79]
4 studies · 92 participants
Very low

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

0.5% bupivacaine, 1:200,000 epinephrine may leads to higher speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 3.32 [0.27, 6.37]
2 studies · 63 participants
Low

4% prilocaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% prilocaine, 1:200,000 epinephrine may leads to higher success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 4% articaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
RR 1.74 [1.16, 2.60]
2 studies · 78 participants
Low

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

4% articaine, 1:200,000 epinephrine showed no clear difference in success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 4% articaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
RR 0.97 [0.87, 1.08]
5 studies · 248 participants
Low

4% articaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes speed of onset of anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 0.19 [-2.06, 2.45]
2 studies · 40 participants
Very low

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

0.5% bupivacaine, 1:200,000 epinephrine showed no clear difference in success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
RR 0.80 [0.62, 1.05]
3 studies · 90 participants
Low