Findings

What do systematic reviews say?

2,509 questions · 2,666 findings · 288 reviews

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No studies found 743 · 27.9%GRADE not reported 327 · 12.3%Very low 775 · 29.1%Low 484 · 18.2%Moderate 279 · 10.5%High 58 · 2.2%

Radiotherapy vs surgical excision

Pain · adults with basal cell carcinoma of the skin

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Radiotherapy vs surgical excision

Early treatment failure · adults with basal cell carcinoma of the skin

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MAL‐PDT vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

MAL‐PDT may leads to higher recurrence at 3 years compared with surgical excision (low certainty).

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 26.47 [1.63, 429.92]
1 study · 68 participants
Low

MAL‐PDT vs surgical excision

Cosmesis · adults with basal cell carcinoma of the skin

MAL‐PDT probably leads to higher cosmetic outcome (excellent/good) compared with surgical excision (moderate certainty).

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 1.18 [1.09, 1.27]
2 studies · 309 participants
Moderate

MAL‐PDT vs surgical excision

Pain · adults with basal cell carcinoma of the skin

MAL‐PDT showed no clear difference in pain compared with surgical excision (low certainty).

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 2.2 [0.6, 8.03]
1 study · 101 participants
Low

MAL‐PDT vs surgical excision

Early treatment failure · adults with basal cell carcinoma of the skin

MAL‐PDT probably leads to higher early treatment failure compared with surgical excision (moderate certainty).

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 6.66 [1.22, 36.41]
2 studies · 173 participants
Moderate

Mohs micrographic surgery vs surgical excision

Cosmesis · adults with basal cell carcinoma of the skin

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

Mohs micrographic surgery vs surgical excision

Pain · adults with basal cell carcinoma of the skin

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mohs micrographic surgery vs surgical excision

Early treatment failure · adults with basal cell carcinoma of the skin

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Imiquimod vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Imiquimod probably leads to higher recurrence at 3 years compared with surgical excision (moderate certainty).

2 findings from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 10.3 [3.22, 32.94]
1 study · 401 participants
Moderate
Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 7.73 [2.81, 21.3]
1 study · 383 participants
Moderate

Imiquimod vs surgical excision

Cosmetic outcome (good/excellent) · adults with basal cell carcinoma of the skin

Imiquimod may leads to higher cosmetic outcome (good/excellent) compared with surgical excision (low certainty).

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 1.7 [1.35, 2.15]
1 study · 344 participants
Low

Imiquimod vs surgical excision

Number of patients with moderate/severe pain (1 hour postoperatively) · adults with basal cell carcinoma of the skin

Imiquimod showed no clear difference in pain (moderate/severe) compared with surgical excision (low certainty).

1 finding from 1 review

Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
RR 1.36 [0.98, 1.88]
1 study · 443 participants
Low

Laxative plus bulking agent vs laxative alone

Pain or straining on defecation · postpartum women who underwent surgical repair of third degree perineal tears

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 147 participants
Very low

Laxative plus bulking agent vs laxative alone

Incidence of postpartum constipation · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative plus bulking agent vs laxative alone

Quality of life · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative plus bulking agent vs laxative alone

Time from completion of operation to first bowel movement (hours) · postpartum women who underwent surgical repair of third degree perineal tears

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 147 participants
Very low

Laxative plus bulking agent vs laxative alone

Adverse effects on women: faecal incontinence during first 10 postpartum days · postpartum women who underwent surgical repair of third degree perineal tears

It is very uncertain whether laxative plus bulking agent changes adverse effects on women: faecal incontinence during first 10… compared with laxative alone (very low certainty).

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
RR 1.81 [1.01, 3.23]
1 study · 147 participants
Very low

Laxative plus bulking agent vs laxative alone

Adverse effects on babies · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Subcuticular sutures vs surgical tapes

Wound complications · skin closure in non‐obstetric surgery

Subcuticular sutures showed no clear difference in wound complications Incidence of wound complications compared with surgical tapes (low certainty).

1 finding from 1 review

Subcuticular sutures for skin closure in non‐obstetric surgery 2020 · Cochrane Headline outcomes only
RR 0.9 [0.61, 1.34]
5 studies · 492 participants
Low

Subcuticular sutures vs surgical tapes

Wound dehiscence · skin closure in non‐obstetric surgery

It is very uncertain whether subcuticular sutures changes wound dehiscence Incidence of wound dehiscence compared with surgical tapes (very low certainty).

1 finding from 1 review

Subcuticular sutures for skin closure in non‐obstetric surgery 2020 · Cochrane Headline outcomes only
RR 0.07 [0, 1.47]
4 studies · 264 participants
Very low