Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,509 questions · 2,666 findings · 288 reviews

No studies found 743 · 27.9%GRADE not reported 327 · 12.3%Very low 775 · 29.1%Low 484 · 18.2%Moderate 279 · 10.5%High 58 · 2.2%

Multidisciplinary inpatient rehabilitation vs usual care

Greater dependence in personal activities of daily livingg · older people undergoing rehabilitation soon after surgically treated hip fracture

It is very uncertain whether multidisciplinary inpatient rehabilitation changes greater dependence in personal activities of daily livingg compared with usual care (very low certainty).

2 findings from 1 review

Multidisciplinary inpatient rehabilitation vs usual care

Greater dependency in mobility (e.g. requiring help by another person) · older people undergoing rehabilitation soon after surgically treated hip fracture

Multidisciplinary inpatient rehabilitation may leads to lower greater dependency in mobility (e.g. requiring help by another person) compared with usual care (low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ pelvic pain · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ pelvic pain compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ ovarian cyst · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ ovarian cyst compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Adverse events ‐ depression · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).

1 finding from 1 review

Raloxifene vs placebo

Biopsy‐proven recurrence of endometriosis · women with endometriosis, following complete surgical excision of lesions

It is very uncertain whether raloxifene changes biopsy‐proven recurrence of endometriosis compared with placebo (very low certainty).

1 finding from 1 review

Combined index tests (e.g. vital staining plus light-based detection or cytology) vs Surgical or punch biopsy with histological assessment

Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review

Light-based detection and/or oral spectroscopy (e.g. ViziLite, VELscope, Microlux DL, Identafi 3000) vs Surgical or punch biopsy with histological assessment

Sensitivity · Adults (aged 16 years or over) presenting to primary or secondary care with clinically evident suspicious or innocuous oral lesions
1 finding from 1 review

Mohs micrographic surgery vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Mohs micrographic surgery showed no clear difference in recurrence at 3 years compared with surgical excision (low certainty).

2 findings from 1 review

Radiotherapy vs surgical excision

Recurrence · adults with basal cell carcinoma of the skin

Radiotherapy may leads to higher recurrence at 3 years compared with surgical excision (with or without frozen section margin control) (low certainty).

2 findings from 1 review

Radiotherapy vs surgical excision

Cosmetic outcome (good/excellent) · adults with basal cell carcinoma of the skin

Radiotherapy probably leads to lower cosmetic outcome (good/excellent) compared with surgical excision (with or without frozen section margin control) (moderate certainty).

1 finding from 1 review