Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Intervention not reported

Change in disability after one year · people with chronic inflammatory demyelinating polyradiculoneuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Change in impairment after 12 weeks (excluding those who did not complete the study) NIS score (range 0 to 280) · people with chronic inflammatory demyelinating polyradiculoneuropathy
1 finding from 1 review

Intervention not reported

Change in impairment after 12 weeks (including those who did not complete the study) NIS (range 0 to 280) · people with chronic inflammatory demyelinating polyradiculoneuropathy
1 finding from 1 review

Intervention not reported

Number of participants improved after 12 weeks (excluding those who did not complete the study) NIS score (range 0 to 280) · people with chronic inflammatory demyelinating polyradiculoneuropathy

It is very uncertain whether the intervention changes number of participants improved after 12 weeks (excluding those who… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants improved after 12 weeks (including those who did not complete the study) NIS (range 0 to 280) · people with chronic inflammatory demyelinating polyradiculoneuropathy

It is very uncertain whether the intervention changes number of participants improved after 12 weeks (including those who… (very low certainty).

1 finding from 1 review

Monthly pulsed high‐dose dexamethasone vs prednisolone

≥ 1 point improvement on INCAT disability score at 12 months · patients with chronic inflammatory demyelinating polyradiculoneuropathy

Monthly pulsed high‐dose dexamethasone may leads to higher ≥ 1 point improvement on INCAT disability score at 12 months compared with oral prednisolone (low certainty).

1 finding from 1 review

Methotrexate vs placebo

Participants able to reduce corticosteroid or IVIg dose by more than 20% · people with CIDP

Methotrexate showed no clear difference in participants able to reduce corticosteroid or IVIg dose by more than… compared with placebo (moderate certainty).

1 finding from 1 review