Intervention not reported
Incidence of adverse events ‐ overall · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ overall (moderate certainty).
1 finding from 1 review
Intervention not reported
Incidence of adverse events ‐ co‐trimoxazole prophylaxis only · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ co‐trimoxazole prophylaxis only (moderate certainty).
1 finding from 1 review
Intervention not reported
Incidence of adverse events ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ isoniazid prophylaxis only (moderate certainty).
1 finding from 1 review
Intervention not reported
Incidence of Pseudomonas infection in children with cystic fibrosis ‐ ciprofloxacin prophylaxis only · children with cystic fibrosis aged 12 years and under
The intervention showed no clear difference in incidence of Pseudomonas infection in children with cystic fibrosis… (moderate certainty).
1 finding from 1 review
Intervention not reported
Mean FEV1 % predicted · children with cystic fibrosis aged 12 years and under
1 finding from 1 review
Probable early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in probable early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Serious maternal outcome · pregnant women with prelabour rupture of membranes at or near term
1 finding from 1 review
Probable early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes probable early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Definite early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in definite early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Definite early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes definite early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).
1 finding from 1 review
Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term
It is very uncertain whether any antibiotic changes maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).
1 finding from 1 review
Stillbirth · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in stillbirth compared with placebo or no antibiotic (low certainty).
1 finding from 1 review
Perinatal mortality · pregnant women with prelabour rupture of membranes at or near term
Any antibiotic showed no clear difference in perinatal mortality compared with placebo or no antibiotic (low certainty).
1 finding from 1 review
Neonatal mortality · pregnant women with prelabour rupture of membranes at or near term
1 finding from 1 review
Fever clearance time · children with acute pyelonephritis
1 finding from 1 review
Increase in serum creatinine during treatment · children with acute pyelonephritis
Different dosing regimens of aminoglycosides (daily showed no clear difference in increase in serum creatinine during treatment compared with 8 hourly) (low certainty).
1 finding from 1 review
Persistent bacteriuria · children with acute pyelonephritis
Agent: Third generation cephalosporin showed no clear difference in persistent bacteriuria compared with other antibiotic (low certainty).
1 finding from 1 review
Recurrent UTI after end of therapy · children with acute pyelonephritis
Agent: Third generation cephalosporin showed no clear difference in recurrent UTI after end of therapy compared with other antibiotic (low certainty).
1 finding from 1 review
Persistent symptoms · children with acute pyelonephritis
Agent: Third generation cephalosporin may leads to lower persistent symptoms after end of treatment compared with other antibiotic (low certainty).
1 finding from 1 review