Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Postoperative mortality · adult participants given general anaesthesia

It is very uncertain whether PEEP changes postoperative mortality compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Pneumonia · adult participants given general anaesthesia

It is very uncertain whether PEEP changes pneumonia compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review

Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia

Death from all causes Range of · patients undergoing primary tumour surgery

Epidural anaesthesia in addition to general anaesthesia showed no clear difference in death from all causes Range of compared with general anaesthesia alone (low certainty).

1 finding from 1 review

Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia

Tumour progression or death from all causes Range of · patients undergoing primary tumour surgery

It is very uncertain whether epidural anaesthesia in addition to general anaesthesia changes tumour progression or death from all causes Range of compared with general anaesthesia alone (very low certainty).

1 finding from 1 review

Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia

Tumour progression Median · patients undergoing primary tumour surgery

It is very uncertain whether epidural anaesthesia in addition to general anaesthesia changes tumour progression Median compared with general anaesthesia alone (very low certainty).

1 finding from 1 review