Findings

What do systematic reviews say?

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Intervention not reported

Foot alignmentPirani score. Scale from: 0 to 6. A lower score indicates better alignment · participants with CTEV at initial presentation

1 finding from 1 review

Interventions for congenital talipes equinovarus (clubfoot) 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

Foot alignment Pirani score. A lower score indicates better alignment. Scale from: 0 to 6. · participants with CTEV (type of case (i.e. whether initial presentation or relapsed) not specified)

1 finding from 1 review

Interventions for congenital talipes equinovarus (clubfoot) 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… probably leads to lower anaemia (haemoglobin values lower than 110 g/L) compared with no intervention or placebo (moderate certainty).

1 finding from 1 review

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
RR 0.82 [0.76, 0.9]
16 studies · 9927 participants
Moderate

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… showed no clear difference in anaemia (haemoglobin values lower than 110 g/L) compared with an iron‐only supplement (low certainty).

1 finding from 1 review

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
RR 0.89 [0.58, 1.39]
1 study · 145 participants
Low

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

Uterine fibroid‐related symptoms (duration of uterine bleeding, measured at 12 weeks; lower = better) · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

LNG‐IUS vs oral progestogen (norethisterone acetate)

Change in fibroid related symptoms · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Acupuncture vs no treatment

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 163 participants
Very low

Acupressure vs sham control

Pain intensity (0‐10cm visual analogue scale) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 472 participants
Very low

Acupressure vs usual care

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 620 participants
Very low

Carboplatin vs cisplatin chemotherapy

Overall survival (baseline risks for low‐ and high‐risk groups in the control arm were estimated at 1 year) · combination with third‐generation drugs for advanced non‐small cell lung cancer

Carboplatin showed no clear difference in overall survival (baseline risks for low‐ and high‐risk groups in… compared with cisplatin chemotherapy (high certainty).

1 finding from 1 review

Cisplatin versus carboplatin in combination with third‐generation drugs for advanced non‐small cell lung cancer 2020 · Cochrane Headline outcomes only
HR 0.99 [0.82, 1.2]
10 studies · 2515 participants
High

Anti‐VEGF vs steroids

Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · people with BRVO

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 343 participants
Moderate

Anti‐VEGF vs sham

Mean central retinal thickness (CRT) change at 6 months in microns (lower value is better) · macular oedema secondary to branch retinal vein occlusion

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 281 participants
Moderate

Anti‐VEGF vs laser

Mean central retinal thickness (CRT) change at 6 months in microns (lower value is better) · people with BRVO

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 201 participants
Moderate

tDCS vs active control

Secondary outcome measure: lower extremity function at the end of · people with stroke

2 findings from 1 review

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 66 participants
Moderate
Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

tDCS vs placebo or control

Secondary outcome measure: lower extremity function at the end of · people with stroke

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 204 participants
Moderate

Intervention not reported

PIPP (maximum score within 3 minutes following lancing) · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

Stratum corneum hydration (SCH) (at baseline and day 56 ± 4) Hahnel 2017: measured at 56 ± 4 days in mid‐volar arm and lower leg in arbitrary units from 0 (no water) to 120 (on water) using the Corneometer CM 825 Gillis 2016: measured at 12 weeks ... · people 60 years of age and older

1 finding from 1 review

Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 266 participants
Very low

Simulation‐based obstetric team training vs no training

Low Apgar score

Simulation‐based obstetric team training showed no clear difference in low Apgar score (Kirkpatrick level 4: patient outcome) compared with no training (low certainty).

1 finding from 1 review

Multi‐professional simulation‐based team training in obstetric emergencies for improving patient outcomes and… 2020 · Cochrane Headline outcomes only
RR 0.99 [0.85, 1.15]
2 studies · 115171 participants
Low

rHuEPO with iron vs control treatment with or without iron

Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO low (150 to 300 IU/kg BW) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia

1 finding from 1 review

Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing… 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 334 participants
Low