Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,432 questions · 1,467 findings · 116 reviews · Headline outcomes only

No studies found 232 · 15.8%GRADE not reported 202 · 13.8%Very low 286 · 19.5%Low 327 · 22.3%Moderate 286 · 19.5%High 134 · 9.1%

Vitamin D plus calcium vs vitamin D

Healing of rickets (number) Definition: normal alkaline phosphatase and bone radiograph

Vitamin D plus calcium may leads to higher healing of rickets (number) Definition: normal alkaline phosphatase… compared with vitamin D (low certainty).

1 finding from 1 review

Abiraterone + ADT vs ADT only

Adverse events grade 3 to 5 Range of · men with metastatic, hormone‐sensitive prostate cancer

Abiraterone + ADT leads to higher grades III to V adverse events (severe and life threatening, as per… compared with ADT alone (high certainty).

1 finding from 1 review

Abiraterone + ADT vs ADT only

Time to death from prostate cancerMedian · men with metastatic, hormone‐sensitive prostate cancer

Abiraterone + ADT probably leads to lower time to death due to prostate cancer measured at a median compared with ADT alone (moderate certainty).

1 finding from 1 review

Abiraterone + ADT vs ADT only

Discontinued treatment due to adverse events measured at a median · men with metastatic, hormone‐sensitive prostate cancer

Abiraterone + ADT probably leads to higher discontinued treatment due to adverse events measured at a median compared with ADT alone (moderate certainty).

1 finding from 1 review

Intervention not reported

Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic

The intervention showed no clear difference in microfilaraemia (mf) prevalence (high certainty).

1 finding from 1 review

Intervention not reported

Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic

The intervention showed no clear difference in microfilaraemia (mf) prevalence (moderate certainty).

1 finding from 1 review