Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Lithium vs clonazepam

Efficacy: response (categorical) YMRS change ≥ 50% from baseline to end of study · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs clonazepam

Efficacy : remission (categorical) YMRS ≤ 12 at end of study · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs ECT

Efficacy: response (categorical) YMRS change ≥ 50% from baseline to end of study · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs ECT

Remission · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs all antimanic agents

Efficacy: response (categorical) YMRS/MRS/BPRS change by ≥ 50% at end of study · acute mania

Lithium leads to higher efficacy: response (categorical) YMRS/MRS/BPRS change by ≥ 50% at… compared with all antimanic agents (high certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 1.36 [1.01, 1.83]
    14 studies · 3666 participants
    High

Lithium vs valproate

Efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end of study · acute mania

Lithium showed no clear difference in efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end… compared with valproate (moderate certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 1.22 [0.87, 1.7]
    5 studies · 607 participants
    Moderate

Exercise vs NSAIDs

Restriction of daily life activities ‐ not reported · young women with suspected primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Exercise vs no treatment

Restriction of daily life activities ‐ not reported · young women with suspected primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Proteinuric pre‐eclampsia · pregnant women considered to be at risk of developing pre‐eclampsia

The intervention leads to lower proteinuric pre‐eclampsia (high certainty).

1 finding from 1 review

Amifostine vs no otoprotective intervention

Ototoxicity according to NCI CTC v2 criteria with intravenous platinum (combined asymptomatic and symptomatic disease) Objective and subjective audiometric evaluations were performed, no further information provided · children with cancer treated with platinum‐based therapy

Amifostine showed no clear difference in ototoxicity according to NCICTCv2 criteria with intravenous platinum… compared with no otoprotective intervention (low certainty).

1 finding from 1 review

Intervention not reported

Any anxiety STAI‐S (Blanchard 1996). POMS Anxiety subscale (Bultz 2000; Campbell 2007). HADS‐A (Nicolaisen 2018; Robertson 2016). Additional study (reported in comments section): SCL‐90‐R Anxiety subscale (Heinrich 1985). Higher scores indicate hi... · informal caregivers of people affected by cancer
1 finding from 1 review