Intraoperative blood loss (mL) · adults and children with chronic rhinosinusitis with or without nasal polyps
1 finding from 1 review
Significant adverse events (seizures, thromboembolism) within 24 hours of surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in significant adverse events (seizures, thromboembolism) within 24… compared with placebo (saline solution or sterile water) (moderate certainty).
1 finding from 1 review
Duration of surgery (minutes) Assessed as: total surgical time · adults and children with chronic rhinosinusitis with or without nasal polyps
1 finding from 1 review
Incomplete surgery · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in incomplete surgery compared with placebo (saline solution or sterile water) (moderate certainty).
1 finding from 1 review
Overall rate of surgical complications · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in surgical complications compared with placebo (saline solution or sterile water) (moderate certainty).
1 finding from 1 review
Postoperative bleeding (place of packing or revision surgery within 14 days of surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in postoperative bleeding (place of packing or revision surgery within… compared with placebo (saline solution or sterile water) (low certainty).
1 finding from 1 review
Treatment success as defined by the authors · children (4 to 18 years) with functional abdominal pain disorders
Probiotic may leads to higher treatment success (at study end, as reported by study authors) compared with placebo (low certainty).
1 finding from 1 review
Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).
1 finding from 1 review
Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether synbiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes complete resolution of pain (at study end, as reported by study… compared with placebo (very low certainty).
1 finding from 1 review
Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).
1 finding from 1 review
Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes frequency of pain (at study end, episodes per week) compared with placebo (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Treatment success as defined by the authors · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic may leads to higher treatment success (at study end, as reported by study authors) compared with placebo (low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic showed no clear difference in complete resolution of pain (at study end, as reported by study… compared with placebo (low certainty).
1 finding from 1 review