Findings

What do systematic reviews say?

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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NSAIDs vs no intervention

Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery

1 finding from 1 review

Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

NSAIDs vs placebo

Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery

1 finding from 1 review

Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 310 participants
Low

NSAIDs vs other analgesics

Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery

1 finding from 1 review

Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 200 participants
Low

Intervention vs usual care

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · COPD and at least one other long‐term condition

1 finding from 1 review

Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 70 participants
Low

Intervention vs usual care

Quality of life ‐ CAT · COPD and at least one other long‐term condition

1 finding from 1 review

Tailored or adapted interventions for adults with chronic obstructive pulmonary disease and at least one other… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Low

Comparison #3: Decision coaching plus evidence‐based information vs usual care ‐ Summary of findings

Feeling uninformed subscale of Decisional conflict Scale (O'Connor 1995b) measured post‐consultation (Deschamps 2004)

It is very uncertain whether comparison #3: Decision coaching plus evidence‐based information changes feeling uninformed subscale of Decisional Conflict Scale (O'Connor… compared with usual care ‐ Summary of findings (very low certainty).

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 212 participants
Very low

Comparison #3: Decision coaching plus evidence‐based information vs usual care ‐ Summary of findings

Unclear values

It is very uncertain whether comparison #3: Decision coaching plus evidence‐based information changes unclear values subscale of Decisional Conflict Scale (O'Connor… compared with usual care ‐ Summary of findings (very low certainty).

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
SMD 0.02
3 studies · 212 participants
Very low

Comparison #3: Decision coaching plus evidence‐based information vs usual care ‐ Summary of findings

Feeling unsupported

It is very uncertain whether comparison #3: Decision coaching plus evidence‐based information changes feeling unsupported subscale of Decisional Conflict Scale (O'Connor… compared with usual care ‐ Summary of findings (very low certainty).

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 212 participants
Very low

Comparison #3: Decision coaching plus evidence‐based information vs evidence‐based information ‐ Summary of findings

Feeling uninformed subscale of Decisional conflict Scale (O'Connor 1995b) measured post‐consultation (Deschamps 2004)

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Very low

Comparison #3: Decision coaching plus evidence‐based information vs evidence‐based information ‐ Summary of findings

Unclear values

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Very low

Comparison #3: Decision coaching plus evidence‐based information vs evidence‐based information ‐ Summary of findings

Feeling unsupported

1 finding from 1 review

Decision coaching for people making healthcare decisions 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Very low

Screws vs fixed angle plates

Function WOMAC function (range 17 to 85) ( · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced

1 finding from 1 review

Internal fixation implants for intracapsular hip fractures in older adults 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 498 participants
Low

Screws or pins vs fixed angle plates

Function WOMAC function (range 17 to 85) ( · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced

1 finding from 1 review

Internal fixation implants for intracapsular hip fractures in older adults 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 498 participants
Low

Anti‐IL‐4Rα mAb (dupilumab) vs placebo (on top of topical steroids)

Disease‐specific quality of life · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 784 participants
High

Anti‐IL‐5 mAb (mepolizumab) vs placebo (on top of topical steroids)

Disease severity ‐ VAS (range 0 to 10, lower = better) · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 72 participants
Very low

Anti‐IL‐5 mAb (mepolizumab) vs placebo (on top of topical steroids)

Extent of disease ‐ CT scan (lower score = better) · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low

Anti‐IgE mAb (omalizumab) vs placebo (on top of topical steroids)

Disease‐specific quality of life · patients with chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 265 participants
Moderate

Anti‐IL‐4Rα mAb (dupilumab) vs placebo (on top of topical steroids)

Disease severity ‐ VAS (range 0 to 10, lower = better) · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 784 participants
Moderate

Anti‐IgE mAb (omalizumab) vs placebo (on top of topical steroids)

Extent of disease ‐ endoscopic score · patients with chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 312 participants
Low

Anti‐IgE mAb (omalizumab) vs placebo (on top of topical steroids)

Extent of disease ‐ CT scan (lower score = better) · patients with chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 47 participants
Very low