Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Intervention not reported

Lower limb compression vs control · women having spinal anaesthesia for caesarean section

It is very uncertain whether the intervention changes lower limb compression vs control (very low certainty).

1 finding from 1 review

Phlebotonics vs placebo?

Oedema in the lower legs (dichotomous variable) · patients with venous insufficiency

Do phlebotonics improve signs and symptoms of venous insufficiency… probably leads to lower oedema in the lower legs (dichotomous variable) compared with placebo? (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

DSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in DSSI ‐ low infection risk environment compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

All wound infections (SSSI + DSSI) ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ low infection risk environment compared with placebo (very low certainty).

2 findings from 1 review

Antibiotic prophylaxis vs placebo

SSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in SSSI ‐ low infection risk environment compared with placebo (moderate certainty).

1 finding from 1 review

Radiotherapy combined with anti‐VEGF vs anti‐VEGF alone

Change in visual acuity (logMAR) ‐ 12 months (negative is better) · people with neovascular AMD

Radiotherapy combined with anti‐VEGF showed no clear difference in change in best corrected visual acuity (logMAR units) Measured using… compared with anti‐VEGF alone (low certainty).

1 finding from 1 review

Brief psychotherapeutic intervention vs usual care

Reduction in physical signs As assessed by SDQ‐20 (lower is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

It is very uncertain whether brief psychotherapeutic intervention changes reduction in physical signs As assessed by SDQ‐20 (lower is better) compared with standard care (very low certainty).

1 finding from 1 review