Post‐operative apnoea with preoperative sedatives excluded · Preterm infants requiring surgery for inguinal hernia in early infancy
Regional (spinal, epidural, caudal) probably leads to lower post‐operative apnoea with preoperative sedatives excluded compared with general anaesthesia (moderate certainty).
1 finding from 1 review
Anaesthetic agent failure · Preterm infants requiring surgery for inguinal hernia in early infancy
Regional (spinal, epidural, caudal) may leads to higher anaesthetic agent failure compared with general anaesthesia (low certainty).
1 finding from 1 review
Anaesthetic placement failure · Preterm infants requiring surgery for inguinal hernia in early infancy
Regional (spinal, epidural, caudal) showed no clear difference in anaesthetic placement failure compared with general anaesthesia (low certainty).
1 finding from 1 review
Intervention not reported
Inhospital case fatality rate · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in inhospital case fatality rate (moderate certainty).
1 finding from 1 review
Intervention not reported
Pneumonia · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in pneumonia (low certainty).
1 finding from 1 review
Intervention not reported
Pulmonary atelectasis · adult patients 18 years and above undergoing standard general anaesthesia
The intervention leads to higher pulmonary atelectasis (high certainty).
1 finding from 1 review
Intervention not reported
Myocardial infarction · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in myocardial infarction (high certainty).
1 finding from 1 review
Intervention not reported
Stroke · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in stroke (moderate certainty).
1 finding from 1 review
Intervention not reported
Severe nausea and vomiting · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in severe nausea and vomiting (low certainty).
1 finding from 1 review
Intervention not reported
Length of hospital stay · adult patients 18 years and above undergoing standard general anaesthesia
1 finding from 1 review
Intervention not reported
Venous thromboembolism · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in venous thromboembolism (moderate certainty).
1 finding from 1 review
Intervention not reported
Wound infection rate · adult patients 18 years and above undergoing standard general anaesthesia
The intervention showed no clear difference in wound infection rate (low certainty).
1 finding from 1 review
Shivering · people with surgical requirement for general anaesthesia
It is very uncertain whether alpha‐2 adrenergic agonist changes shivering compared with placebo/control (very low certainty).
1 finding from 1 review
Incidence of core hypothermia ‐ not measured · people with surgical requirement for general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant satisfaction/experience of shivering ‐ not measured · people with surgical requirement for general anaesthesia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Sedation (sedative agents administered via any route) vs General anaesthesia
Outcome not reported · Children and adolescents younger than 18 years having dental treatment (fillings, pulp treatment or tooth extraction); complex surgical…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review
Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review
Because of substantial clinical and methodological heterogeneity in the studies, we were unable to determine an estimate of effect
1 study · 54 participants
Very low
Lip or cheek biting, numbness or allergy · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review
Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
The review found no eligible studies for this question.
1 finding from 1 review