Cochrane · systematic review · CD008984
Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia
Sun, R, Jia, WQ, Zhang, P, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 33.3%Moderate 4 · 44.4%High 2 · 22.2%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings’ table 1
Population: adult patients 18 years and above undergoing standard general anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Inhospital case fatality rate | OR 0.87 [0.61, 1.26] | 8 studies · 10148 participants | Moderate Downgraded: imprecision |
Pneumonia | OR 1.68 [1, 2.81] | 8 studies · 2699 participants | Low Downgraded: risk of bias, imprecision |
Pulmonary atelectasis | OR 1.57 [1.18, 2.1] | 5 studies · 2400 participants | High |
Myocardial infarction | OR 1.01 [0.84, 1.22] | 6 studies · 9246 participants | High |
Stroke | OR 1.47 [0.86, 2.53] | 4 studies · 9142 participants | Moderate Downgraded: imprecision |
Severe nausea and vomiting | OR 1.44 [0.97, 2.15] | 10 studies · 11045 participants | Low Downgraded: risk of bias, inconsistency |
Length of hospital stay | no estimate extracted | 6 studies · 1103 participants | Moderate Downgraded: inconsistency |
'Summary of findings' table 2
Population: adult patients 18 years and above undergoing standard general anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Venous thromboembolism | OR 0.73 [0.45, 1.2] | 2 studies · 9004 participants | Moderate Downgraded: imprecision |
Wound infection rate | OR 1.22 [0.84, 1.78] | 6 studies · 9789 participants | Low Downgraded: imprecision, inconsistency |