Cochrane · systematic review · CD011107

Alpha‐2 adrenergic agonists for the prevention of shivering following general anaesthesia

Lewis, SR, Nicholson, A, Smith, AF, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
1
No studies
2
Included studies
NR
No studies 2 · 66.7%Ungraded 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Alpha‐2 adrenergic agonist compared to placebo/control for the prevention of shivering following general anaesthesia

Population: people with surgical requirement for general anaesthesia
3 questions
OutcomeEffectEvidenceStatus / GRADE
Shivering
Alpha‐2 adrenergic agonist vs placebo/control
RR 0.28 [0.18, 0.43]20 studies · 1391 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Incidence of core hypothermia ‐ not measured
Alpha‐2 adrenergic agonist vs placebo/control
no estimate extractedNRNo studies
Participant satisfaction/experience of shivering ‐ not measured
Alpha‐2 adrenergic agonist vs placebo/control
no estimate extractedNRNo studies