Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,938 questions · 1,994 findings · 246 reviews · Headline outcomes only

No studies found 490 · 24.6%GRADE not reported 71 · 3.6%Very low 669 · 33.6%Low 446 · 22.4%Moderate 264 · 13.2%High 54 · 2.7%

Enteral vs enteral and parenteral nutrition

Number of ICU‐free days up to day 28 · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Heparin‐induced thrombocytopenia (HIT) · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower heparin‐induced thrombocytopenia (HIT) (low certainty).

1 finding from 1 review

Intervention not reported

HIT complicated by venous thromboembolism · people undergoing surgical procedures and treated with UFH or LMWH for prophylaxis of thrombotic events lasting at least 5 days

The intervention may leads to lower HIT complicated by venous thromboembolism (low certainty).

1 finding from 1 review

LOD vs other surgical interventions

Harms: Adhesions at 6 months ‐ LOD vs THL N of participants: 246 (1 RCT) · Women with symptoms of PCOS

It is very uncertain whether LOD changes harms: Adhesions at 6 months ‐ LOD vs THL N of participants: 246 (1… compared with other surgical interventions (very low certainty).

1 finding from 1 review

LOD vs other surgical interventions

Menstrual regularity at 12 months Laser LOD vs harmonic scalpel N of participants: 34 (1 RCT) · Women with symptoms of PCOS

LOD showed no clear difference in menstrual regularity at 6 months ‐ LOD vs ultrasound‐guided… compared with other surgical interventions (low certainty).

2 findings from 1 review

LOD vs other surgical interventions

Improvement in androgenic symptoms at 6 months (Acne) ‐ LOD vs USS guided N of participants:31 (1 RCT) · Women with symptoms of PCOS

LOD showed no clear difference in improvement in androgenic symptoms at 6 months (Acne) ‐ LOD vs USS… compared with other surgical interventions (low certainty).

1 finding from 1 review

LOD vs other surgical interventions

Improvement in androgenic symptoms at 6 months (Hirsutism) ‐ LOD vs USS‐guided N of participants: 39 (1 RCT) · Women with symptoms of PCOS

LOD showed no clear difference in improvement in androgenic symptoms at 6 months (Hirsutism) ‐ LOD vs… compared with other surgical interventions (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events related to RIPC · patients undergoing a surgical intervention that induces kidney injury

The intervention showed no clear difference in adverse events related to RIPC (high certainty).

1 finding from 1 review

Intervention not reported

Acute kidney injury defined by AKIN · patients undergoing a surgical intervention that induces kidney injury

The intervention showed no clear difference in acute kidney injury defined by AKIN (high certainty).

1 finding from 1 review

Bioabsorbable vs metallic interference screws

Functional ability · Adults undergoing surgical reconstruction of a ruptured ACL1
3 findings from 1 review

Bioabsorbable vs metallic interference screws

Overall treatment failure ‐ Intraoperative and postoperative complications5 · Adults undergoing surgical reconstruction of a ruptured ACL1

It is very uncertain whether bioabsorbable changes overall treatment failure ‐ Intraoperative and postoperative… compared with metallic interference screws (very low certainty).

1 finding from 1 review

Bioabsorbable vs metallic interference screws

Overall treatment failure ‐ Postoperative complications7 · Adults undergoing surgical reconstruction of a ruptured ACL1

It is very uncertain whether bioabsorbable changes overall treatment failure ‐ Postoperative complications7 compared with metallic interference screws (very low certainty).

1 finding from 1 review

Bioabsorbable vs metallic interference screws

Activity level: Tegner score ( 0 to 10; higher scores = greater activity) · Adults undergoing surgical reconstruction of a ruptured ACL1
2 findings from 1 review

Intervention not reported

Cumulative pain score from the end of operation (0 hours) to 72 hours · adults aged ≥ 18 years undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review