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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

767 questions in 53 reviews · Back and Neck

current versions
No studies 149 · 19.4%Ungraded 41 · 5.3%Very low 168 · 21.9%Low 226 · 29.5%Moderate 156 · 20.3%High 27 · 3.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Disability Multiple scales (0 to 100) Intermediate · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted4 studies · 348 participantsModerate
Intervention NR
Pain VAS (0 to 100) Intermediate · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted6 studies · 588 participantsHigh
Intervention NR
Disability Multiple scales (0 to 100) Long‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted3 studies · 279 participantsModerate
Intervention NR
Adverse events · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain VAS (0 to 100) Short‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted2 studies · 68 participantsLow
Intervention NR
Pain VAS (0 to 100) Intermediate · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted2 studies · 179 participantsVery low
Intervention NR
Disability Multiple scales (0 to 100) Short‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted1 study · 38 participantsVery low
Intervention NR
Disability Multiple scales (0 to 100) Intermediate · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted1 study · 38 participantsLow
Intervention NR
Adverse events · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain VAS (0 to 100) Long‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted5 studies · 643 participantsHigh
Intervention NR
Disability Multiple scales (0 to 100) Short‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted11 studies · 794 participantsLow
Intervention NR
Disability Multiple scales (0 to 100) Intermediate · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted6 studies · 588 participantsHigh
Intervention NR
Disability Multiple scales (0 to 100) Long‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted4 studies · 570 participantsHigh
Intervention NR
Adverse events · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain VAS (0 to 100) Short‐term · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted3 studies · 282 participantsModerate
Intervention NR
Pain VAS (0 to 100) Intermediate · patients with non‐specific chronic low back pain
Motor control exercise for chronic non‐specific low‐back pain (2016) · Cochrane
no estimate extracted4 studies · 485 participantsModerate
Intervention NR
Pain VAS (0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 58 participantsLow
Intervention NR
Adverse events None of the included studies evaluated adverse events · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain VAS (0 to 100) · patients with acute LBP
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 41 participantsVery low
Intervention NR
Disability Roland Morris Disability Questionnaire (transformed 0 to 100) · patients with acute LBP
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 41 participantsVery low
Intervention NR
Recurrence · patients with acute LBP
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
RR 0.36 [0.18, 0.72]1 study · 39 participantsVery low
Intervention NR
Adverse events None of the included studies evaluated adverse events · patients with acute LBP
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Disability Oswestry Disability Index (0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 85 participantsLow
Intervention NR
Disability Oswestry Disability Index (0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 85 participantsLow
Intervention NR
Adverse events None of the included studies evaluated adverse events · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pain VAS (0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted2 studies · 89 participantsModerate
Intervention NR
Pain VAS (0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 33 participantsLow
Intervention NR
Disability Multiple scales (transformed 0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted2 studies · 116 participantsModerate
Intervention NR
Disability Roland Morris Disability Questionnaire (transformed 0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 33 participantsLow
Intervention NR
Disability Oswestry Disability Index (0 to 100) · patients with acute low back pain
Motor control exercise for acute non‐specific low back pain (2016) · Cochrane
no estimate extracted1 study · 83 participantsLow
Intervention NR
Change in pain intensity from baseline 100 mm VAS · people with chronic low back pain
Non‐steroidal anti‐inflammatory drugs for chronic low back pain (2016) · Cochrane
no estimate extracted6 studies · 1354 participantsLow
Intervention NR
Change in disability from baseline RDQ 0 to 24 · people with chronic low back pain
Non‐steroidal anti‐inflammatory drugs for chronic low back pain (2016) · Cochrane
no estimate extracted4 studies · 1161 participantsLow
Intervention NR
Proportion of participants experiencing adverse events · people with chronic low back pain
Non‐steroidal anti‐inflammatory drugs for chronic low back pain (2016) · Cochrane
RR 1.04 [0.92, 1.17]6 studies · 1354 participantsLow
Intervention NR
Sensitivity analysis: change in pain intensity from baseline 100 mm VAS · people with chronic low back pain
Non‐steroidal anti‐inflammatory drugs for chronic low back pain (2016) · Cochrane
no estimate extracted3 studies · 728 participantsModerate
Intervention NR
Sensitivity analysis: change in disability from baseline RDQ 0 to 24 · people with chronic low back pain
Non‐steroidal anti‐inflammatory drugs for chronic low back pain (2016) · Cochrane
no estimate extracted2 studies · 654 participantsModerate
Intervention NR
Sensitivity analysis: proportion of participants experiencing adverse events. · people with chronic low back pain
Non‐steroidal anti‐inflammatory drugs for chronic low back pain (2016) · Cochrane
RR 0.93 [0.81, 1.07]3 studies · 728 participantsModerate
Paracetamol vs placebo
Pain 1 week (immediate term) (NRS 0 to 100) · People with acute low back pain
Paracetamol for low back pain (2016) · Cochrane
no estimate extracted1 study · 1520 participantsHigh
Paracetamol vs placebo
Pain 12 weeks (short term) (NRS 0 to 100) · People with acute low back pain
Paracetamol for low back pain (2016) · Cochrane
no estimate extracted1 study · 1526 participantsHigh
Paracetamol vs placebo
Disability 1 week (immediate term) (RMDQ 0 to 24) · People with acute low back pain
Paracetamol for low back pain (2016) · Cochrane
no estimate extracted1 study · 1511 participantsHigh
Paracetamol vs placebo
Disability 12 weeks (short term) (RMDQ 0 to 24) · People with acute low back pain
Paracetamol for low back pain (2016) · Cochrane
no estimate extracted1 study · 1522 participantsHigh
Paracetamol vs placebo
Any adverse events Up to 12 weeks' · People with acute low back pain
Paracetamol for low back pain (2016) · Cochrane
RR 1.07 [0.86, 1.33]1 study · 1624 participantsHigh
Paracetamol vs placebo
Serious adverse events Up to 12 weeks' · People with acute low back pain
Paracetamol for low back pain (2016) · Cochrane
RR 0.9 [0.3, 2.67]1 study · 1643 participantsModerate
NSAIDs vs placebo
Change in pain intensity from baseline on VAS (0 to 100) short‐term · people with low back pain with sciatica
Non‐steroidal anti‐inflammatory drugs for sciatica (2016) · Cochrane
no estimate extracted3 studies · 918 participantsVery low
NSAIDs vs placebo
Change in disability from baseline to · people with low back pain with sciatica
Non‐steroidal anti‐inflammatory drugs for sciatica (2016) · Cochrane
no estimate extracted1 study · 214 participantsVery low
NSAIDs vs placebo
Global Improvement short‐term · people with low back pain with sciatica
Non‐steroidal anti‐inflammatory drugs for sciatica (2016) · Cochrane
RR 1.143 studies · 753 participantsLow
NSAIDs vs placebo
Side effects short‐term · people with low back pain with sciatica
Non‐steroidal anti‐inflammatory drugs for sciatica (2016) · Cochrane
RR 1.44 studies · 967 participantsLow
SUMMARY OF FINDINGS FOR DECOMPRESSION vs FUSION
Pain Long‐term (≥ 12 months) Pain scores converted to 0 to 100 scale to allow for comparison of different disability scales (VAS, NRS) · patients with lumbar spinal stenosis
Surgical options for lumbar spinal stenosis (2016) · Cochrane
no estimate extracted4 studies · 380 participantsVery low
SUMMARY OF FINDINGS FOR DECOMPRESSION vs INTERSPINOUS SPACERS
Reoperations Number of patients requiring a revision surgery · patients with lumbar spinal stenosis
Surgical options for lumbar spinal stenosis (2016) · Cochrane
Risk ratio 0.25 [0.14, 0.47]3 studies · 326 participantsHigh
SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS
Pain Long‐term (≥ 12 months) Pain scores converted to 0 to 100 scale to allow for comparison of different disability scales (VAS, NRS) · patients with lumbar spinal stenosis
Surgical options for lumbar spinal stenosis (2016) · Cochrane
Mean difference 5.352 studies · 308 participantsLow
SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS
Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar spinal stenosis
Surgical options for lumbar spinal stenosis (2016) · Cochrane
Mean difference 5.72 [1.28, 10.15]2 studies · 308 participantsLow