Cochrane · systematic review · CD012382
Non‐steroidal anti‐inflammatory drugs for sciatica
Rasmussen‐Barr, E, Held, U, Grooten, WJA, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
NSAIDs compared with placebo for low back pain with sciatica
Population: people with low back pain with sciatica
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in pain intensity from baseline on VAS (0 to 100) short‐term NSAIDs vs placebo | no estimate extracted | 3 studies · 918 participants | Very low Downgraded: risk of bias, inconsistency |
Change in disability from baseline to NSAIDs vs placebo | no estimate extracted | 1 study · 214 participants | Very low Downgraded: risk of bias, inconsistency |
Global Improvement short‐term NSAIDs vs placebo | RR 1.14 | 3 studies · 753 participants | Low Downgraded: risk of bias, inconsistency |
Side effects short‐term NSAIDs vs placebo | RR 1.4 | 4 studies · 967 participants | Low Downgraded: risk of bias, inconsistency |