What do systematic reviews say?

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.45 [0.19, 1.04]
  3 studies · 191 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.46, 1.46]
  5 studies · 395 participants
  Low

Topical quinolone vs quinolones

Topical quinolone may leads to higher resolution of ear discharge ‐ 1 to 2 weeks compared with oral quinolone (low certainty).

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  RR 1.48 [1.24, 1.76]
  3 studies · 285 participants
  Low

Topical quinolone vs intramuscular gentamicin

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs intramuscular gentamicin

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Topical quinolone vs intramuscular gentamicin

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Topical quinolone vs intramuscular gentamicin

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Topical quinolone vs intramuscular gentamicin

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

It is very uncertain whether topical quinolone changes resolution of ear discharge ‐ 1 to 2 weeks compared with oral amoxicillin‐clavulanic acid combination (very low certainty).

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  RR 2.93 [1.5, 5.72]
  1 study · 56 participants
  Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 56 participants
  Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 56 participants
  Very low

Topical quinolone vs quinolones

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 56 participants
  Very low

Topical quinolone vs quinolones

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs quinolones

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs quinolones

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs quinolones

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found