Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

158 questions · 174 findings · 22 reviews · Gut

No studies found 20 · 11.5%GRADE not reported 7 · 4%Very low 79 · 45.4%Low 31 · 17.8%Moderate 25 · 14.4%High 12 · 6.9%

Intervention not reported

Treatment withdrawal · people with pancreatic surgery

It is very uncertain whether the intervention changes treatment withdrawal (very low certainty).

1 finding from 1 review

Intervention not reported

Re‐operation · people with pancreatic surgery

It is very uncertain whether the intervention changes re‐operation (very low certainty).

1 finding from 1 review

Intervention not reported

Anastomotic leak · people with pancreatic surgery

The intervention showed no clear difference in anastomotic leak; GRADE not reported.

1 finding from 1 review

Intervention not reported

Pancreatic fistula (clinically significant) · people with pancreatic surgery

It is very uncertain whether the intervention changes pancreatic fistula (clinically significant) (very low certainty).

1 finding from 1 review

Intervention not reported

Infected abdominal collections · people with pancreatic surgery

The intervention showed no clear difference in infected abdominal collections; GRADE not reported.

1 finding from 1 review

Intervention not reported

Shock · people with pancreatic surgery

The intervention showed no clear difference in shock; GRADE not reported.

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Quality of life · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Clinical recurrence (until week 102) · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes clinical recurrence (until week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Surgical recurrence ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review