Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

260 questions · 357 findings · 37 reviews · Dental caries

No studies found 24 · 6.7%GRADE not reported 257 · 72%Very low 37 · 10.4%Low 27 · 7.6%Moderate 4 · 1.1%High 8 · 2.2%

Bottle-feeding only vs Breastfeeding only

Early childhood caries (ECC) · Healthy children under 6 years in South Africa

No significant difference in caries odds was found between bottle-fed-only and breast-fed-only children (meta-analysis reported no difference; pooled estimate in an unavailable supplementary figure; not GRADE-rated).

1 finding from 1 review

Low parental socioeconomic status (SES) vs High parental socioeconomic status (SES)

Early childhood caries (ECC) · Healthy children under 6 years in South Africa

No significant difference in caries odds was found between children of low- versus high-SES parents (meta-analysis reported no difference; pooled estimate in an unavailable supplementary figure; not GRADE-rated).

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population (children and adults) in East Africa

Caries prevalence in permanent dentition (>=12 years) was 50.2% (95% CI 38.4 to 62.1); certainty not graded.

1 finding from 1 review

Poor / no tooth brushing habit vs Good tooth brushing habit

Dental caries · Individuals in East Africa assessed for dental caries

Poor tooth brushing was associated with significantly higher odds of dental caries (OR 1.967, 95% CI 1.205 to 3.211); certainty not graded.

1 finding from 1 review

Frequent carbohydrate / sugary food intake vs Infrequent carbohydrate intake

Dental caries · Individuals in East Africa assessed for dental caries

Frequent carbohydrate intake was associated with significantly higher odds of dental caries (OR 1.575, 95% CI 1.13 to 3.051); certainty not graded.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population (children and adults) in East Africa

Caries prevalence in mixed dentition (6-12 years) was 41.3% (95% CI 33.5 to 49.2); certainty not graded.

1 finding from 1 review

Intervention not reported

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals with permanent dentition in East Africa

The pooled mean DMFT (permanent dentition) in East Africa was 1.941 (95% CI 1.561 to 2.322); certainty not graded.

1 finding from 1 review