Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

120 questions · 120 findings · 15 reviews · Headline outcomes only

No studies found 32 · 26.7%GRADE not reported 3 · 2.5%Very low 34 · 28.3%Low 31 · 25.8%Moderate 18 · 15%High 2 · 1.7%

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Neonatal mortality · neonates with fast breathing alone

Comparison 2: 7 days oral amoxicillin showed no clear difference in neonatal mortality compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).

1 finding from 1 review

Comparison 2: 7 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin

Treatment failure · neonates with fast breathing alone

Comparison 2: 7 days oral amoxicillin showed no clear difference in treatment failure compared with 7 days injectable benzylpenicillin + injectable gentamicin (low certainty).

1 finding from 1 review