Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

394 questions · 412 findings · 112 reviews

No studies found 51 · 12.4%GRADE not reported 41 · 10%Very low 86 · 20.9%Low 121 · 29.4%Moderate 84 · 20.4%High 29 · 7%

Intervention not reported

Mean oxygen tension (mm Hg) in umbilical artery (UaPO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

Mean oxygen tension (mm Hg) in umbilical vein (UvPO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Nasal prongs vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with acute lower respiratory tract infections

It is very uncertain whether nasal prongs changes treatment failure Failure to achieve adequate oxygenation (SaO2) compared with nasopharyngeal catheter (very low certainty).

1 finding from 1 review

Mask vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

Face mask may leads to lower treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (low certainty).

1 finding from 1 review

Head box vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

It is very uncertain whether head box changes treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (very low certainty).

1 finding from 1 review

Hypothermic oxygenated perfusion (HOPE) vs static cold storage (SCS)

Ischaemic biliary complications (donated following brain death (DBD)) · liver transplant recipients

Hypothermic oxygenated perfusion (HOPE) showed no clear difference in ischaemic biliary complications (donated following brain death (DBD)) compared with static cold storage (SCS); GRADE not reported.

1 finding from 1 review

Hypothermic oxygenated perfusion (HOPE) vs static cold storage (SCS)

Ischaemic biliary complications (donated following circulatory death (DCD)) · liver transplant recipients

Hypothermic oxygenated perfusion (HOPE) led to lower ischaemic biliary complications (donated following circulatory death… compared with static cold storage (SCS); GRADE not reported.

1 finding from 1 review

Oxygen‐guided lung‐recruitment maneuver vs usual care

Death at hospital discharge · preterm infants < 37 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

Oxygen‐guided lung‐recruitment maneuver showed no clear difference in mortality by hospital discharge compared with routine care (low certainty).

1 finding from 1 review

Oxygen‐guided lung‐recruitment maneuver vs usual care

Bronchopulmonary dysplasia · preterm infants < 37 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

Oxygen‐guided lung‐recruitment maneuver showed no clear difference in bronchopulmonary dysplasia compared with routine care (low certainty).

1 finding from 1 review

Oxygenated glycerol triester (OGT) spray vs Saliveeze (aqueous electrolyte) spray

Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

Oxygenated glycerol triester (OGT) spray led to higher xerostomia (mouth dryness scale) compared with saliveeze (aqueous electrolyte) spray; GRADE not reported.

1 finding from 1 review