What do systematic reviews say?

Zinc vs placebo

It is very uncertain whether summary of findings: Zinc supplementation changes need for antibiotics number of days on IV or oral antibiotics compared with placebo (very low certainty).

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  MD 0.52
  2 studies · 62 participants
  Very low

Pine bark extract vs control

• Pine bark (Pinus spp.) extract for treating chronic disorders 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Pine bark extract vs control

• Pine bark (Pinus spp.) extract for treating chronic disorders 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Intervention not reported

• Growth hormone therapy for people with thalassaemia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Moderate

Dietary advice vs oral nutritional supplements

The review found no eligible studies for this question.

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dietary advice vs oral nutritional supplements

The review found no eligible studies for this question.

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dietary advice vs oral nutritional supplements

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 517 participants
  Low

Dietary advice vs oral nutritional supplements

The review found no eligible studies for this question.

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dietary advice vs oral nutritional supplements

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 283 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

Dietary advice showed no clear difference in mortality compared with dietary advice plus oral nutritional supplements (low certainty).

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  RR 0.92 [0.47, 1.8]
  10 studies · 777 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

Dietary advice may leads to higher number of people admitted or re‐admitted to hospital compared with dietary advice plus oral nutritional supplements (low certainty).

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  RR 1.7 [1.04, 2.77]
  1 study · 114 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 202 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

Dietary advice may leads to lower complications compared with dietary advice plus oral nutritional supplements (low certainty).

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  RR 0.75 [0.56, 0.99]
  3 studies · 317 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 931 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 187 participants
  Low

Dietary advice vs dietary advice plus oral nutritional supplements

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 321 participants
  Low

Dietary advice vs oral nutritional supplements

Dietary advice showed no clear difference in mortality compared with oral nutritional supplements (low certainty).

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  RR 0.66 [0.34, 1.26]
  8 studies · 576 participants
  Low

Dietary advice vs oral nutritional supplements

Dietary advice showed no clear difference in number of people admitted or re‐admitted to hospital compared with oral nutritional supplements (low certainty).

• Dietary advice with or without oral nutritional supplements for disease‐related malnutrition in adults 2021 · Cochrane Headline outcomes only
  RR 0.36 [0.04, 3.24]
  1 study · 50 participants
  Low

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)

The review found no eligible studies for this question.

• Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease… 2019 · Cochrane All outcomes
  This outcome was not reported in either of the trials.
  0 studies
  No studies found

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)

The review found no eligible studies for this question.

• Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease… 2019 · Cochrane All outcomes
  No randomised or quasi-randomised controlled trials in people with Von Willebrand disease met the inclusion criteria; no eligible VWD trials were identified.
  0 studies
  No studies found