Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

166 questions · 178 findings · 15 reviews

No studies found 52 · 29.2%GRADE not reported 1 · 0.6%Very low 44 · 24.7%Low 56 · 31.5%Moderate 24 · 13.5%High 1 · 0.6%

Gonadotrophins with anti‐oestrogens vs gonadotropins alone

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Gonadotrophins with anti‐oestrogens showed no clear difference in multiple pregnancy rate per couple compared with gonadotropins alone (low certainty).

1 finding from 1 review

Gonadotrophins with anti‐oestrogens vs gonadotropins alone

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotrophins with anti‐oestrogens changes clinical pregnancy rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Oestrogen therapy alone vs placebo

Venous thrombo‐embolism (DVT or PE): CEE 0.625 mg (moderate dose) · relatively healthy postmenopausal women

Oestrogen‐only hormone therapy (HT) showed no clear difference in venous thromboembolism (DVT or PE): CEE 0.625 mg (moderate dose) compared with placebo (moderate certainty).

1 finding from 1 review