Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

230 questions · 235 findings · 17 reviews

No studies found 71 · 30.2%GRADE not reported 17 · 7.2%Very low 70 · 29.8%Low 49 · 20.9%Moderate 20 · 8.5%High 8 · 3.4%

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Combination of lidocaine intraperitoneal instillation plus… showed no clear difference in number of women requiring rescue medication compared with lidocaine intraperitoneal instillation alone (low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative pain or discomfort (dichotomous data) · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Need for additional anaesthesia during surgery Assessed dichotomously, as 'additional anaesthesia given' or 'additional anaesthesia not given' · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in need for additional anaesthesia during surgery Assessed… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative adverse surgical events attributable to choice of anaesthesia · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in intraoperative adverse surgical events attributable to choice of… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

Intervention not reported

High‐intensity pain with lidocaine admixture Pain scales · Adult participants receiving propofol for induction of anaesthesia

The intervention leads to lower high‐intensity pain with lidocaine admixture Pain scales (high certainty).

1 finding from 1 review

Intervention not reported

High‐intensity pain with lidocaine pretreatment Pain scales · Adult participants receiving propofol for induction of anaesthesia

The intervention leads to lower high‐intensity pain with lidocaine pretreatment Pain scales (high certainty).

1 finding from 1 review

Intervention not reported

Incidence of pain with lidocaine admixture Pain scales · Adult participants receiving propofol for induction of anaesthesia

The intervention leads to lower incidence of pain with lidocaine admixture Pain scales (high certainty).

1 finding from 1 review

Intervention not reported

Incidence of pain with lidocaine pretreatment Pain scales · Adult participants receiving propofol for induction of anaesthesia

The intervention leads to lower incidence of pain with lidocaine pretreatment Pain scales (high certainty).

1 finding from 1 review

Intraperitoneal lidocaine instillation vs IM morphine

Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia

Intraperitoneal lidocaine instillation may leads to lower number of women requiring rescue medication compared with intramuscular morphine (low certainty).

1 finding from 1 review