Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

467 questions · 495 findings · 30 reviews · Pregnancy and Childbirth

No studies found 124 · 25.1%GRADE not reported 48 · 9.7%Very low 104 · 21%Low 134 · 27.1%Moderate 62 · 12.5%High 23 · 4.6%

Dopamine antagonists vs placebo

Nausea · women undergoing regional anaesthesia for caesarean section

It is very uncertain whether dopamine antagonists changes nausea ‐ intraoperative compared with placebo (very low certainty).

2 findings from 1 review

Healthcare professional‐led breastfeeding education and support vs usual care

Breastfeeding initiation · women exposed to interventions intended to promote breastfeeding

Healthcare professional‐led breastfeeding education and support may leads to higher initiation of breastfeeding compared with standard care (low certainty).

1 finding from 1 review

Non‐healthcare professional‐led breastfeeding education and support vs usual care

Breastfeeding initiation · women exposed to interventions intended to promote breastfeeding

Non‐healthcare professional‐led breastfeeding education and support may leads to higher initiation of breastfeeding compared with standard care (low certainty).

1 finding from 1 review

Non‐healthcare professional‐led breastfeeding education and support vs usual care

Early initiation of breastfeeding · women exposed to interventions intended to promote breastfeeding

It is very uncertain whether non‐healthcare professional‐led breastfeeding education and support changes early initiation of breastfeeding compared with standard care (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Recurrent pyelonephritis · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes recurrent pyelonephritis compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Recurrent UTI (cystitis) · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes recurrent UTI (cystitis) compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Preterm birth · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes preterm birth (< 37 weeks) compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Birthweight < 2500 (g) · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes birthweight < 2500 (g) compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Apgar score less than 7 at 5 minutes · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes five‐minute Apgar score < seven compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Miscarriage · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes miscarriages compared with close surveillance alone (very low certainty).

1 finding from 1 review