Cochrane · systematic review · CD011448

Interventions for treating constipation in pregnancy

Rungsiprakarn, P, Laopaiboon, M, Sangkomkamhang, US, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
5
No studies
4
Included studies
NR
No studies 4 · 36.4%Ungraded 2 · 18.2%Very low 0 · 0%Low 1 · 9.1%Moderate 4 · 36.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Stimulant laxatives versus bulk‐forming laxatives for treating constipation in pregnancy

Population: women with treating constipation in pregnancy
7 questions
OutcomeEffectEvidenceStatus / GRADE
Primary outcome ‐ constipation improvement
Stimulant laxatives vs bulk‐forming laxatives
RR 1.59 [1.21, 2.09]1 study · 140 participantsModerate
Downgraded: risk of bias
Primary outcome ‐ pain on defecation ‐ not reported
Stimulant laxatives vs bulk‐forming laxatives
no estimate extractedNRNo studies
Primary outcome ‐ frequency of stools
Stimulant laxatives vs bulk‐forming laxatives
no estimate extracted0 studies · 2 participantsUngraded
Primary outcome ‐ consistency of stools
Stimulant laxatives vs bulk‐forming laxatives
no estimate extracted0 studies · 2 participantsUngraded
Secondary outcome ‐ abdominal discomfort
Stimulant laxatives vs bulk‐forming laxatives
RR 2.33 [1.15, 4.73]1 study · 140 participantsModerate
Downgraded: risk of bias
Secondary outcome ‐ diarrhoea
Stimulant laxatives vs bulk‐forming laxatives
RR 4.5 [1.01, 20.09]1 study · 140 participantsLow
Downgraded: risk of bias
Secondary outcome ‐ women's satisfaction
Stimulant laxatives vs bulk‐forming laxatives
RR 1.06 [0.77, 1.46]1 study · 140 participantsModerate
Downgraded: risk of bias

Fibre supplementation versus no intervention for treating constipation in pregnancy

Population: Women being treated for constipation in pregnancy
4 questions
OutcomeEffectEvidenceStatus / GRADE
Primary outcome ‐ frequency of stools
Fibre supplementation vs no intervention
no estimate extracted1 study · 40 participantsModerate
Downgraded: risk of bias
Primary outcome ‐ pain on defecation ‐ not reported
Fibre supplementation vs no intervention
no estimate extractedNRNo studies
Primary outcome ‐ improvement in constipation ‐ not reported
Fibre supplementation vs no intervention
no estimate extractedNRNo studies
Primary outcome ‐ consistency of stools ‐ not reported
Fibre supplementation vs no intervention
no estimate extractedNRNo studies