Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

192 questions · 196 findings · 21 reviews · Headline outcomes only

No studies found 48 · 24.5%GRADE not reported 5 · 2.6%Very low 80 · 40.8%Low 38 · 19.4%Moderate 16 · 8.2%High 9 · 4.6%

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Mental health outcomes · women aged 40 to 75 years at average to moderate risk of breast cancer

Studies focused only on enhanced communication, without… showed no clear difference in mental health outcomes compared with control (high certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening IVR versus enhanced usual care at median · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention showed no clear difference in behavioural outcome: breast cancer screening IVR versus enhanced… (moderate certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression recovery ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

Lay health worker‐led psychosocial interventions may leads to higher recovery from depression ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · women with perinatal depression
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Functional impairment · women with perinatal depression

Lay health worker‐led psychosocial interventions showed no clear difference in functional impairment ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Service utilisation ‐ maternal or child hospitalisations ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

It is very uncertain whether lay health worker‐led psychosocial interventions changes service utilisation ‐ maternal or child hospitalisations ‐… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Depressive symptoms · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes depression symptoms ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review