Cochrane · systematic review · CD013294
Automated oxygen delivery for preterm infants with respiratory dysfunction
Stafford, IG, Lai, NM, Tan, K · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
4
No studies
8
Included studies
NR
No studies 8 · 66.7%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 25%Moderate 1 · 8.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Automated oxygen delivery compared to routine manual oxygen delivery for preterm infants with respiratory dysfunction
Population: preterm infants with respiratory dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time in desired SpO2 rangeScale: 0% to 100% of time Automated oxygen delivery vs routine manual oxygen delivery | no estimate extracted | 11 studies · 284 participants | Moderate Downgraded: risk of bias |
All‐cause in‐hospital mortality by 36 weeks' postmenstrual ageUnit: number of infants with event Automated oxygen delivery vs routine manual oxygen delivery | no estimate extracted | NR | No studies |
Severe ROPUnit: number of infants with event Automated oxygen delivery vs routine manual oxygen delivery | RR 0.24 [0.03, 1.94] | 1 study · 39 participants | Low Downgraded: imprecision |
Neurodevelopmental outcomes at approximately 2 years' corrected age Automated oxygen delivery vs routine manual oxygen delivery | no estimate extracted | NR | No studies |
Automated oxygen delivery compared to enhanced manual oxygen delivery for preterm infants with respiratory dysfunction
Population: preterm infants with respiratory dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time in desired SpO2 rangeScale: 0% to 100% of time Automated oxygen delivery vs enhanced manual oxygen delivery | no estimate extracted | 2 studies · 19 participants | Low Downgraded: risk of bias, imprecision |
All‐cause in‐hospital mortality by 36 weeks' postmenstrual ageUnit: number of infants with event Automated oxygen delivery vs enhanced manual oxygen delivery | no estimate extracted | NR | No studies |
Severe ROPUnit: number of infants with event Automated oxygen delivery vs enhanced manual oxygen delivery | no estimate extracted | NR | No studies |
Neurodevelopmental outcomes at approximately 2 years' corrected age Automated oxygen delivery vs enhanced manual oxygen delivery | no estimate extracted | NR | No studies |
CLACfast compared to CLACslow for preterm infants with respiratory dysfunction
Population: preterm infants with respiratory dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time in desired SpO2 rangeScale: 0% to 100% of time CLACfast vs CLACslow | no estimate extracted | 1 study · 19 participants | Low Downgraded: risk of bias, imprecision |
All‐cause in‐hospital mortality by 36 weeks' postmenstrual ageUnit: number of infants with event CLACfast vs CLACslow | no estimate extracted | NR | No studies |
Severe ROPUnit: number of infants with event CLACfast vs CLACslow | no estimate extracted | NR | No studies |
Neurodevelopmental outcomes at approximately 2 years' corrected age CLACfast vs CLACslow | no estimate extracted | NR | No studies |