Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

270 questions · 320 findings · 28 reviews

No studies found 58 · 18.1%GRADE not reported 96 · 30%Very low 86 · 26.9%Low 55 · 17.2%Moderate 16 · 5%High 9 · 2.8%

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Confidence in the decision made · women aged 40 to 75 years at average to moderate risk of breast cancer

Studies focused only on enhanced communication, without… showed no clear difference in confidence in the decision made compared with control (low certainty).

1 finding from 1 review

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Knowledge of all the options · women aged 40 to 75 years at average to moderate risk of breast cancer

Studies focused only on enhanced communication, without… leads to higher knowledge of all the options*** compared with control (high certainty).

1 finding from 1 review

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Choice of an option aligned with each woman’s values and preferences · women aged 40 to 75 years at average to moderate risk of breast cancer

The review found no eligible studies for this question.

1 finding from 1 review

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Mental health outcomes · women aged 40 to 75 years at average to moderate risk of breast cancer

Studies focused only on enhanced communication, without… showed no clear difference in mental health outcomes compared with control (high certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening IVR versus enhanced usual care at median · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention showed no clear difference in behavioural outcome: breast cancer screening IVR versus enhanced… (moderate certainty).

1 finding from 1 review

Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

In the fully within-person analysis, visual classification had a summary sensitivity of 0.82 (95% CrI 0.73, 0.89); ungraded.

2 findings from 1 review

Transillumination and OCT vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

Transillumination and OCT had a summary specificity of 0.82 (95% CrI 0.68, 0.91) for detecting enamel caries; low certainty.

1 finding from 1 review

Fluorescence-based devices vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

In the fully within-person analysis, fluorescence had a summary specificity of 0.88 (95% CrI 0.78, 0.94); ungraded.

2 findings from 1 review