Question · asked by 1 review
Fluorescence-based devices vs Reference standard (histology, excavation, or enhanced visual examination): Specificity for detection of enamel caries
- Population
- Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
- Intervention
- Fluorescence-based devices
- Comparison
- Reference standard (histology, excavation, or enhanced visual examination)
- Outcome
- Specificity for detection of enamel caries
In the fully within-person analysis, fluorescence had a summary specificity of 0.88 (95% CrI 0.78, 0.94); ungraded.
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Fluorescence-based devices vs Reference standard (histology, operative excavation, or enhanced visual examination) Specificity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · General dental practice; in vitro (extracted teeth) and in vivo (clinical) studies, Analysis 1: fully within-person comparison (studies evaluating >=3 index tests) In the fully within-person analysis, fluorescence had a summary specificity of 0.88 (95% CrI 0.78, 0.94); ungraded. Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews. (2022) All outcomes | Specificity 0.88 [0.78, 0.94] | 19 studies · 2849 participants | GRADE not reported |
Fluorescence-based devices vs Reference standard (histology, operative excavation, or enhanced visual examination) Specificity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · General dental practice; in vitro (extracted teeth) and in vivo (clinical) studies, Analysis 2: network meta-analysis (all studies evaluating >=2 index tests) Fluorescence-based devices had a summary specificity of 0.83 (95% CrI 0.75, 0.89) for detecting enamel caries; low certainty. Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews. (2022) All outcomes | Specificity 0.83 [0.75, 0.89] | 64 studies · 24567 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews. 2022 All outcomes | Not specified | Not listed | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.