Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,192 questions · 1,243 findings · 151 reviews

No studies found 252 · 20.3%GRADE not reported 180 · 14.5%Very low 291 · 23.4%Low 282 · 22.7%Moderate 174 · 14%High 64 · 5.1%

Intervention not reported

Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain

The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).

1 finding from 1 review

AFI vs SDVP: summary of findings table

Admission to neonatal intensive care unit · pregnant women to prevent adverse pregnancy outcome

AFI showed no clear difference in admission to neonatal intensive care unit compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

AFI vs SDVP: summary of findings table

Rate of diagnosis of oligohydramnios · pregnant women to prevent adverse pregnancy outcome

AFI probably leads to higher rate of diagnosis of oligohydramnios compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

AFI vs SDVP: summary of findings table

Caesarean delivery for fetal distress · pregnant women to prevent adverse pregnancy outcome

AFI probably leads to higher caesarean delivery for fetal distress compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride mouthrinse

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride mouthrinse

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride mouthrinse combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride mouthrinse alone; GRADE not reported.

1 finding from 1 review

Fluoride gel combined with fluoride mouthrinse vs Fluoride gel

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride gel combined with fluoride mouthrinse showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride gel alone; GRADE not reported.

1 finding from 1 review

Fluoride mouthrinse, gel or varnish combined with fluoride toothpaste (any combined regimen) vs Fluoride toothpaste alone

Adverse effects (tooth staining and other side effects) · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride varnish combined with fluoride toothpaste vs Fluoride varnish

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride varnish combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride varnish alone; GRADE not reported.

1 finding from 1 review