evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,261 questions · 1,287 findings · 210 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 256 · 19.9%GRADE not reported 123 · 9.6%Very low 248 · 19.3%Low 403 · 31.3%Moderate 208 · 16.2%High 49 · 3.8%

Antipsychotics vs placebo

Dropout · patients with the treatment of cocaine dependence

Any antipsychotic probably leads to lower dropouts Number of participants who dropped out from the study compared with placebo (moderate certainty).

1 finding from 1 review

Antipsychotics vs placebo

Participants with at least some Side Effects · patients with the treatment of cocaine dependence

Any antipsychotic showed no clear difference in side effects Number of participants with at least i side effect compared with placebo (low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Number of participants using cocaine during the treatment (as days/week by urine tests or self report) Number of participants that reported the use of cocaine during the treatment · patients with the treatment of cocaine dependence

Any antipsychotic showed no clear difference in number of participants using cocaine during the treatment (as… compared with placebo (low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Continuous abstinence (number of participants who maintained negative drug screens for 2 ‐ 3 weeks) Number of participants that maintained negative cocaine screens for at least 2 ‐ 3 weeks · patients with the treatment of cocaine dependence

Any antipsychotic showed no clear difference in continuous abstinence (number of participants who maintained… compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Development and worsening of Graves' ophthalmopathy [examination by ophthalmologists]

The intervention may leads to higher development and worsening of Graves' ophthalmopathy [examination by… (low certainty).

1 finding from 1 review

Intervention not reported

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment]

It is very uncertain whether the intervention changes recurrence of hyperthyroidism (relapse) [measured by serum thyroid… (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events other than development or worsening of Graves' disease (a) Hypothyroidism [measured by TSH and/or thyroid hormones] (b) Drug reactions
1 finding from 1 review