Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Intervention not reported

Participation restrictions 100 mm return to usual work activities VAS (higher score reflects better outcome) · people with non‐neurological conditions1
1 finding from 1 review

Intervention not reported

Participation restrictions · people with neurological conditions1

The review found no eligible studies for this question.

1 finding from 1 review

5‐ASA vs control (all trials)

Number of participants with adverse events (epigastric pain, nausea, diarrhoea) · patients with the need for management of diverticulitis

5‐ASA showed no clear difference in number of participants with adverse events (epigastric pain, nausea,… compared with control (all trials) (moderate certainty).

1 finding from 1 review

Intervention not reported

Depression: Geriatric Depression Scale (GDS15) A 15‐item self‐report assessment used to identify depression in the elderly. A yes/no response is required for each item (score 0 or 1). Cummulative score: 0‐4 normal, 5‐9 Mild depression, 10‐15 More ... · adults with stroke
1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Intraventricular haemorrhage, Papile grade 3/4 · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes intraventricular haemorrhage grade III or IV compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Celecoxib vs placebo

Clinical improvement: American College of Rheumatology 20% improvement criteria (ACR20) · patients with rheumatoid arthritis

Celecoxib probably leads to higher clinical improvement: American College of Rheumatology 20%… compared with placebo (moderate certainty).

1 finding from 1 review

Celecoxib vs NSAIDs

Clinical improvement: American College of Rheumatology 20% improvement criteria (ACR20) · patients with rheumatoid arthritis

Celecoxib showed no clear difference in clinical improvement: American College of Rheumatology 20%… compared with traditional NSAIDs (moderate certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life (generic) SF‐36 (Physical Component Summary (PCS) score) Scale from 0‐100 Higher value post intervention is favourable, indicating improvement in health‐related quality of life · people with stable COPD
1 finding from 1 review