Cochrane · systematic review · CD010972
Dietary interventions for recurrent abdominal pain in childhood
Newlove‐Delgado, TV, Martin, AE, Abbott, RA, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Developmental, Psychosocial and Learning ProblemsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 3 · 42.9%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Probiotics compared to placebo for recurrent abdominal pain in childhood
Population: Children with recurrent abdominal pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in pain frequency: 0 to 3 months' postintervention Different measures were used to assess pain frequency, such as a visual analogue scale and the Wong‐Baker FACES Pain Rating Scale (McGrath 1996; Wong 1988). Probiotics vs placebo | no estimate extracted | 6 studies · 523 participants | Low Downgraded: risk of bias, inconsistency |
Change in pain intensity: 0 to 3 months' postintervention Different measures were used to assess pain intensity, as above. Probiotics vs placebo | no estimate extracted | 7 studies · 575 participants | Low Downgraded: risk of bias, inconsistency |
Improvement in pain: 0 to 3 months' postintervention Different measures and definitions were used for improvement in pain, such as Likert scale, visual analogue scale, and Subject’s Global Assessment of Relief Scale (McGrath 1996; Muller‐Lissner 2... Probiotics vs placebo | OR 1.63 [1.07, 2.47] | 7 studies · 722 participants | Moderate Downgraded: inconsistency |
Improvement in pain: 0 to 3 months' postintervention Subgroup (irritable bowel syndrome) Different measures were used to assess improvement in pain, as above. Probiotics vs placebo | OR 3.01 [1.77, 5.13] | 4 studies · 344 participants | Moderate Downgraded: imprecision |
Improvement in pain: 3 to 6 months' postintervention Different measures were used to assess improvement in pain, as above. Probiotics vs placebo | OR 1.94 [1.1, 3.43] | 2 studies · 224 participants | Moderate Downgraded: imprecision |
Fibre versus placebo for recurrent abdominal pain in childhood
Population: Children with recurrent abdominal pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in pain intensity: 0 to 3 months' postintervention Pain intensity was measured using different scales in the 2 included studies: the Wong Baker FACES Pain Rating Scale, Wong 1988, and the Numerical Rating Scale (von Baeyer 2009). Fibre vs placebo | no estimate extracted | 2 studies · 135 participants | Low Downgraded: imprecision, inconsistency |
Improvement in pain: 0 to 3 months' postintervention Improvement in pain was defined and measured differently in the 2 included studies: using a "stomach ache diary" and the Faces Pain Scale (Bieri 1990). Fibre vs placebo | OR 1.83 [0.92, 3.65] | 2 studies · 136 participants | Low Downgraded: risk of bias, imprecision |