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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.
75,239 questions in 5,342 reviews
current versionsNo studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pressure‐garment therapy (PGT) plus silicone vs silicone Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 159 participants | Very low |
Pressure‐garment therapy (PGT) plus silicone vs silicone Pruritus (POSAS 0–10, higher score = more severe pruritus; TPIS 0–3, higher score = more severe pruritus; VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 2 studies · 263 participants | Very low |
Pressure‐garment therapy (PGT) plus silicone vs silicone Quality of life (CHU‐9D 0–1, with 1 representing full health; BBSIP 0–5, higher scores = more severe impact) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 159 participants | Very low |
Pressure‐garment therapy (PGT) plus silicone vs silicone Adverse events · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 159 participants | Very low |
Pressure‐garment therapy (PGT) plus silicone vs silicone Adherence · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 159 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Scar improvement (VSS) (0–14, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
Pressure‐garment therapy (PGT) vs no treatment/lanolin Pain (VAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 104 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Pruritus (POSAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Quality of life (EQ‐5D‐5L 0–1, with 1 representing full health) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Adverse events · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
Pressure‐garment therapy (PGT) plus scar management therapy including silicone vs scar management therapy including silicone Adherence · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 88 participants | Very low |
High‐pressure garment therapy vs low‐pressure garment therapy Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 58 participants | Very low |
High‐pressure garment therapy vs low‐pressure garment therapy Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
High‐pressure garment therapy vs low‐pressure garment therapy Pain · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
High‐pressure garment therapy vs low‐pressure garment therapy Pruritus · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
Pressure‐garment therapy (PGT) vs no treatment/lanolin Pruritus (VAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 104 participants | Very low |
High‐pressure garment therapy vs low‐pressure garment therapy Quality of life · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
High‐pressure garment therapy vs low‐pressure garment therapy Adverse events · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
High‐pressure garment therapy vs low‐pressure garment therapy Adherence · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 67 participants | Very low |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Pain (POSAS 0–10, higher score = more severe pain) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Pruritus (POSAS 0–10, higher score = more severe pruritus) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Quality of life · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Adverse events · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Different types of pressure garment (Caroskin Tricot plus an adhesive silicone gel sheet vs Gecko Nanoplast (silicone gel bandage)) Adherence · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
Pressure‐garment therapy (PGT) vs no treatment/lanolin Quality of life · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
Pressure‐garment therapy (PGT) vs no treatment/lanolin Adverse events · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 1 participants | Ungraded |
Pressure‐garment therapy (PGT) vs no treatment/lanolin Adherence · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | NR | No studies |
Pressure‐garment therapy (PGT) vs silicone Scar improvement (VSS) (0–13, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 96 participants | Very low |
Pressure‐garment therapy (PGT) vs silicone Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring Pressure‐garment therapy for preventing hypertrophic scarring after burn injury (2024) · Cochrane | no estimate extracted | 1 study · 159 participants | Very low |
Intervention NR Finding 12. Physical activity should form part of a treatment plan for both men and women with bipolar disorder. Messaging from professionals tended to concentrate on the benefits of weight loss but did not promote potential mental health benefits... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 12 participants | Moderate |
Intervention NR Finding 13. The enabling role of trained, multidisciplinary professionals was highlighted. Having the right health and social care professionals can deliver a holistic approach to care. Trained mental health professionals involved in physical acti... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 13 participants | Moderate |
Intervention NR Finding 14. Finding the right support could facilitate participation and encourage men and women to be active. Having support, whether from professionals or friends and family, was important. · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 14 participants | Moderate |
Intervention NR Finding 15. Mood regulation is an important aspect of managing symptoms of bipolar disorder, and monitoring mood and physical activity, including the use of technology, may be helpful for men and women with bipolar disorder. This can be used to he... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 15 participants | Moderate |
Intervention NR Finding 16. Accessible, sustainable interventions and finding the right type of exercise were all identified as important. For many women and men with bipolar disorder, the right type of exercise was walking. · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 16 participants | Moderate |
Intervention NR Finding 17. Finding balance, rhythm, structure, and establishing a regular physical activity routine was beneficial. Rhythm and routine brought balance and structure for men and women with bipolar disorder. Incorporating regular physical activity ... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 17 participants | Moderate |
Intervention NR Finding 18: Appropriate coping strategies may support engagement in physical activity and other health‐promoting behaviours. Negative coping mechanisms or a lack of coping strategies for men and women with bipolar disorder can affect engagement. P... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 18 participants | Moderate |
Intervention NR Finding 19: Connecting to nature when undertaking physical activity may convey additional benefits, including increasing the opportunity for social contact, engaging with nature, and reducing stress, that are often associated with spending time ou... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 19 participants | Moderate |
Intervention NR Finding 20. There are some considerations for designing interventions that promote physical activity for bipolar disorder. These include sequencing multicomponent lifestyle changes, technology, incentives, and health promotion strategies that are ... · s where they do not wish or feel the need to participate in physical activity. Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of… (2024) · Cochrane | no estimate extracted | 20 participants | Moderate |
Surgery alone vs pharmacological therapy alone Disease‐related complications · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery alone vs preoperative pharmacological therapy and surgery Adverse events · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | RR 1.23 [0.7, 2.03] | 5 studies · 267 participants | Very low |
Surgery alone vs preoperative pharmacological therapy and surgery All‐cause mortality · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery alone vs preoperative pharmacological therapy and surgery Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | RR 0.48 [0.05, 5.06] | 1 study · 61 participants | Very low |
Surgery alone vs preoperative pharmacological therapy and surgery Non‐surgical therapy for recurrent or persistent diseaseRadiation therapy and/or pharmacologic therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | RR 1.22 [0.65, 2.28] | 2 studies · 100 participants | Very low |
Surgery alone vs preoperative pharmacological therapy and surgery Health‐related quality of life · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery alone vs pharmacological therapy alone Disease recurrence · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surgery alone vs pharmacological therapy alone Adverse events · adults with growth‐hormone secreting pituitary adenomas Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting… (2024) · Cochrane | RR 0.09 [0.01, 1.47] | 1 study · 22 participants | Very low |