Restoration failure · Children with carious primary teeth after vital or non-vital pulp therapy
In one RCT, composite resin had an annual failure rate of 0% after 2 years.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with moderately deep dentine caries in primary molars, no pulp therapy
Etch-and-rinse adhesion failed more than self-etch (19.5% vs 7.0% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Amalgam restorations in primary teeth showed a wide annual failure rate (1-28%) across 4 RCTs; the evidence is of low quality (high risk of bias; ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with severely decayed maxillary primary incisors treated by pulpectomy (non-vital pulp therapy)
Composite strip crowns with composite posts had a low annual failure rate (2.3%) in maxillary primary incisors after pulpectomy (single high-risk-of-bias RCT; low quality of evidence; not GRADE-rated).
3 findings from 1 review
AFR 2.3
1 study · 54 participants
GRADE not reported
AFR 2.2
1 study · 54 participants
GRADE not reported
AFR 0
1 study · 54 participants
GRADE not reported
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
High-viscosity GIC had a wide annual failure rate (2.9-25.6%) and was outperformed by compomer/composite in some trials (3 RCTs); low quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with deep dentine caries in primary molars restored with composite resin (indirect pulp treatment; pulpotomy only if pulp exposed…
Complete caries removal with composite resin had an annual failure rate of 6.8% in primary molars (single high-risk-of-bias RCT; low quality of evidence; not GRADE-rated).
2 findings from 1 review
Restoration failure · Children with carious primary teeth after vital or non-vital pulp therapy
In one RCT, preformed metal crowns had an annual failure rate of 2.5% after 2 years.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with Class-I carious lesions in primary molars, no pulp therapy
A beveled margin lowered composite resin failure (1.8% vs 3.5% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary teeth treated by atraumatic restorative treatment (hand-instrument caries removal), no pulp therapy
ART restorations (mainly GIC) had a wide annual failure rate (1.2-37.1%) across 10 RCTs, with technique affecting survival; low to unclear quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy)
Preformed metal crowns had a low annual failure rate (2.5%) in primary molars after pulpotomy, but the evidence is of low quality (single high-risk-of-bias split-mouth RCT; not GRADE-rated).
2 findings from 1 review
Treatment failure (annual failure rate) · Children (aged 5-8 years) with Class-II caries in primary molars, no pulp therapy
Etching dentine for 7 s rather than 15 s lowered bulk-fill composite failure (5.8% vs 16.9% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children (aged 3-5.5 years) with early childhood caries in anterior primary teeth (>=2 carious surfaces), no pulp therapy
Zirconia crowns failed less than composite strip crowns (3.3% vs 15% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (planned; no eligible studies) · Children with carious primary teeth after vital or non-vital pulp therapy
No eligible studies were found evaluating bio-active restorative materials for restoring carious primary teeth after pulp therapy.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Metal-reinforced GIC had a high annual failure rate (29.9%) in a single RCT; low quality of evidence (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Compomer had an annual failure rate of 0-14.7% (7 RCTs), comparable to amalgam/RMGIC/composite and better than high-viscosity GIC; low quality of evidence (ungraded).
1 finding from 1 review
Health‐related quality of life · patients with chronic obstructive pulmonary disease
1 finding from 1 review
no estimate extracted
2778 participants
Low
Health status ‐ Dyspnoea · patients with chronic obstructive pulmonary disease
1 finding from 1 review
no estimate extracted
356 participants
Low
ED visits · patients with chronic obstructive pulmonary disease
1 finding from 1 review
no estimate extracted
1939 participants
Low
Anxiety and depression · patients with chronic obstructive pulmonary disease
1 finding from 1 review
no estimate extracted
1647 participants
Moderate
FEV1 (% predicted): mean change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review