Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,793 questions · 1,866 findings · 339 reviews

No studies found 245 · 13.1%GRADE not reported 142 · 7.6%Very low 612 · 32.8%Low 513 · 27.5%Moderate 305 · 16.3%High 49 · 2.6%

ACUPUNCTURE added to LOW DOSE ANTIPSYCHOTICS vs STANDARD DOSE ANTIPSYCHOTICS

Mental state: 2. Not improved (BPRS, < 30% decrease in BPRS score) · patients with schizophrenia

It is very uncertain whether ACUPUNCTURE added to LOW DOSE ANTIPSYCHOTICS changes mental state: BPRS (not improved, reduced rate < 30%, short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Loratadine 10 mg vs hydroxyzine 25 mg

Complete suppression of urticaria: short‐term duration of intervention Global assessment of symptom scores · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in complete suppression of urticaria: short‐term duration of… compared with hydroxyzine 25 mg (low certainty).

1 finding from 1 review

SULPIRIDE vs placebo

Mental state: 2. Specific‐ Positive symptoms, total score‐ average endpoint scores (SADS‐C‐PD scale, lower = better) · patients with schizophrenia
1 finding from 1 review

SULPIRIDE vs placebo

Mental state: average score for negative symptoms ‐ by short term Manchester Scale, negative subset endpoint. Scale from: 0 to 20. · patients with schizophrenia
1 finding from 1 review

Hydroxytryptophan vs placebo

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Wessel 1995: Mean syllable duration during rapid‐syllable repetition task. Scale from: 1 to 500. Shorter durations are better. · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review

Riluzole vs placebo

Short‐term (within 1 month) change in isolated movement, objective and subjective measures of speech production Cooper 2008 reported 3 speech measures: ICARS speech subscale. Scale from: 0 to 8. Higher scores indicate greater clinical severity Syl... · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review