Findings

What do systematic reviews say?

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Radiographic joint changes · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Low

Active rPMS only vs no intervention

Lower limb function · people with stroke

The review found no eligible studies for this question.

1 finding from 1 review

Repetitive peripheral magnetic stimulation for impairment and disability in people after stroke 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active rPMS plus rehabilitation vs sham rPMS plus rehabilitation

Lower limb function · people with stroke

The review found no eligible studies for this question.

1 finding from 1 review

Repetitive peripheral magnetic stimulation for impairment and disability in people after stroke 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active rPMS plus rehabilitation vs rehabilitation only

Lower limb function · people with stroke

The review found no eligible studies for this question.

1 finding from 1 review

Repetitive peripheral magnetic stimulation for impairment and disability in people after stroke 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active rPMS only vs sham rPMS

Lower limb function · people with stroke

The review found no eligible studies for this question.

1 finding from 1 review

Repetitive peripheral magnetic stimulation for impairment and disability in people after stroke 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Family‐centred care vs control

Harms · Indigenous children aged < 5 years

1 finding from 1 review

Family‐centred interventions for Indigenous early childhood well‐being by primary healthcare services 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Very low

Whole‐facility changes: Home‐like models vs traditional environment

Global behaviour Neuropsychiatric Inventory (NPI), Neuropsychiatric Inventory‐Nursing Home version (NPI‐NH) and Nurses Observations Scale for Geriatric Patients (NOSGER) (lower scores = better) · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings

1 finding from 1 review

Physical environmental designs in residential care to improve quality of life of older people 2022 · Cochrane Headline outcomes only
no estimate extracted
257 participants
Very low

Whole‐facility changes: Home‐like models vs traditional environment

Depression Revised Memory and Behaviour Problems Checklist (RMBPC) and Mood Scale Score (MSS) (lower scores = better) · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings

1 finding from 1 review

Physical environmental designs in residential care to improve quality of life of older people 2022 · Cochrane Headline outcomes only
no estimate extracted
406 participants
Very low

Whole‐facility changes: Home‐like models vs traditional environment

Activities of daily living · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings

1 finding from 1 review

Physical environmental designs in residential care to improve quality of life of older people 2022 · Cochrane Headline outcomes only
no estimate extracted
499 participants
Very low

Whole‐facility changes: Home‐like models vs traditional environment

Serious adverse effects Physical restraints, reported as percentage points (lower = better) · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings

It is very uncertain whether whole‐facility changes: Home‐like models changes serious adverse effects Physical restraints, reported as percentage… compared with traditional environment (very low certainty).

1 finding from 1 review

Physical environmental designs in residential care to improve quality of life of older people 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74449 participants
Very low

Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)

Venous diameter (high volume versus low volume isotonic exercise training) · CKD patients who underwent AVF creation

1 finding from 1 review

Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 93 participants
Very low

Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)

Blood flow in the inflow artery (isometric versus isotonic exercise training) · CKD patients who underwent AVF creation

1 finding from 1 review

Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 160 participants
Low

Upper limb exercise training vs control (no intervention/usual care/isotonic exercise)

Blood flow in the inflow artery (high volume versus low volume isotonic exercise training) · CKD patients who underwent AVF creation

1 finding from 1 review

Upper limb exercise for arteriovenous fistula maturation in people requiring permanent haemodialysis access 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 15 participants
Very low

Berotralstat vs placebo or active control

Quality of lifeAngioedema Quality of Life scale (lower score is better)(during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 130 participants
Moderate

Berotralstat vs placebo or active control

Disability standardised mean difference (lower is better) (during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Low

C1 esterase inhibitor vs placebo or active control

Improvement in quality of life: the difference in quality of life scores for participants surveyed before and after treatment · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low

Plasma‐derived C1 esterase inhibitor vs placebo or active control

Quality of lifeAngioedema Quality of Life scale (lower score is better)(during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Low

Nanofiltered C1 esterase inhibitor vs placebo or active control

Improvement in quality of life: the difference in quality of life scores for participants surveyed before and after treatment · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Nanofiltered C1 esterase inhibitor vs placebo or active control

Disability standardised mean difference (lower is better) (during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Lanadelumab vs placebo or active control

Differences in quality of life ( · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Low