Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

SUMMARY OF FINDINGS FOR DECOMPRESSION vs fusion

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with lumbar stenosis

It is very uncertain whether SUMMARY OF FINDINGS FOR DECOMPRESSION changes pain Long‐term (≥ 12 months) Pain scores converted to 0 to 100 scale… compared with FUSION (very low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR FUSION showed no clear difference in pain Long‐term (≥ 12 months) Pain scores converted to 0 to 100 scale… compared with INTERSPINOUS SPACERS (low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS

Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR FUSION may leads to higher disability Long‐term (≥ 12 months) Disability scores converted to 0… compared with INTERSPINOUS SPACERS (low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR DECOMPRESSION vs fusion

Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar stenosis

It is very uncertain whether SUMMARY OF FINDINGS FOR DECOMPRESSION changes disability Long‐term (≥ 12 months) Disability scores converted to 0… compared with FUSION (very low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR DECOMPRESSION vs INTERSPINOUS SPACERS

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR DECOMPRESSION showed no clear difference in pain Long‐term (≥ 12 months) Pain scores converted to 0 to 100 scale… compared with INTERSPINOUS SPACERS (moderate certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR DECOMPRESSION vs INTERSPINOUS SPACERS

Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR DECOMPRESSION showed no clear difference in disability Long‐term (≥ 12 months) Disability scores converted to 0… compared with INTERSPINOUS SPACERS (low certainty).

1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)

Orthodontic appliances (palatal crib) led to higher sucking cessation (long term) compared with no treatment; GRADE not reported.

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Prolonged stability of treatment (adjudged using an accepted scale) · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Massage vs inactive control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with LBP
1 finding from 1 review

Massage vs active control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with LBP
1 finding from 1 review

PERPHENAZINE vs antipsychotics

Other adverse events: any serious adverse event ‐ short and long term · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes other adverse events: any serious adverse event ‐ short and long term compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

CBT vs WAIT LIST

Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. · children and adolescents with anxiety disorders

CBT probably leads to higher remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting… compared with wait‐list (moderate certainty).

1 finding from 1 review