Cochrane · systematic review · CD004249
Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment
Gross, A, Langevin, P, Burnie, SJ, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
34
current version
GRADE rated
13
No studies
19
Included studies
NR
No studies 19 · 55.9%Ungraded 2 · 5.9%Very low 0 · 0%Low 2 · 5.9%Moderate 11 · 32.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Manipulation (cervical) compared with oral medicine for acute/subacute neck pain
Population: patients with acute and subacute neck pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PAIN Manipulation (cervical) vs oral medicine | no estimate extracted | NR | No studies |
Acute and subacute neck pain Intermediate‐term Manipulation (cervical) vs oral medicine | no estimate extracted | 1 study · 182 participants | Moderate Downgraded: indirectness |
Acute and subacute neck pain Long‐term Manipulation (cervical) vs oral medicine | no estimate extracted | 1 study · 181 participants | Moderate Downgraded: indirectness |
FUNCTION Manipulation (cervical) vs oral medicine | no estimate extracted | NR | No studies |
PARTICIPANT SATISFACTION Manipulation (cervical) vs oral medicine | no estimate extracted | NR | No studies |
QUALITY OF LIFE Manipulation (cervical) vs oral medicine | no estimate extracted | NR | No studies |
Manipulation (thoracic) compared with inactive control for neck pain
Population: patients with acute, subacute and chronic neck pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PAIN Manipulation (thoracic) vs inactive control | no estimate extracted | NR | No studies |
Acute and subacute neck pain Short‐term Manipulation (thoracic) vs inactive control | no estimate extracted | 4 studies · 242 participants | Moderate Downgraded: imprecision, inconsistency, indirectness |
Chronic neck pain Intermediate‐term Manipulation (thoracic) vs inactive control | no estimate extracted | 1 study · 111 participants | Low Downgraded: indirectness |
FUNCTION Manipulation (thoracic) vs inactive control | no estimate extracted | NR | No studies |
Chronic neck pain Short‐term Manipulation (thoracic) vs inactive control | no estimate extracted | 1 study · 111 participants | Low Downgraded: indirectness |
QUALITY OF LIFE (QoL) Manipulation (thoracic) vs inactive control | no estimate extracted | NR | No studies |
Manipulation compared with mobilisation for neck pain
Population: patients with acute, subacute and chronic neck pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PAIN Manipulation vs mobilisation | no estimate extracted | NR | No studies |
Acute, subacute and chronic neck pain Intermediate‐term Manipulation vs mobilisation | no estimate extracted | 2 studies · 446 participants | Moderate Downgraded: inconsistency |
FUNCTION AND DISABILITY Manipulation vs mobilisation | no estimate extracted | NR | No studies |
Acute and subacute neck pain Short‐term Manipulation vs mobilisation | no estimate extracted | 1 study · 176 participants | Moderate Downgraded: inconsistency, indirectness |
PARTICIPANT SATISFACTION Manipulation vs mobilisation | no estimate extracted | NR | No studies |
Subacute and chronic neck pain Short‐term Manipulation vs mobilisation | no estimate extracted | 1 study · 269 participants | Moderate Downgraded: inconsistency, indirectness |
GLOBAL PERCEIVED EFFECT Manipulation vs mobilisation | no estimate extracted | NR | No studies |
Acute and subacute neck pain Intermediate‐term Manipulation vs mobilisation | no estimate extracted | 1 study · 177 participants | Moderate Downgraded: inconsistency, indirectness |
QUALITY OF LIFE Manipulation vs mobilisation | no estimate extracted | NR | No studies |
Manipulation compared with exercise for neck pain
Population: patients with acute and subacute neck pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PAIN Manipulation vs exercise | no estimate extracted | NR | No studies |
Acute and subacute neck pain Intermediate‐term Manipulation vs exercise | no estimate extracted | 1 study · 182 participants | Moderate Downgraded: indirectness |
Acute and subacute neck pain Long‐term Manipulation vs exercise | SMD 0.06 | 1 study · 182 participants | Moderate Downgraded: indirectness |
FUNCTION Manipulation vs exercise | no estimate extracted | NR | No studies |
PARTICIPANT SATISFACTION Manipulation vs exercise | no estimate extracted | NR | No studies |
GLOBAL PERCEIVED EFFECT Manipulation vs exercise | no estimate extracted | NR | No studies |
Acute and subacute neck pain Immediate post‐treatment Manipulation vs exercise | no estimate extracted | 1 study · 182 participants | Moderate Downgraded: indirectness |
QUALITY OF LIFE Manipulation vs exercise | no estimate extracted | NR | No studies |
aIndirectness: ‐1. Manipulation vs exercise | no estimate extracted | 1 participants | Ungraded |
High dose of manipulation compared with low dose of manipulation for chronic neck pain
Population: patients with chronic neck pain with cervicogenic headache (CGH)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PAIN High dose of manipulation vs low dose of manipulation | no estimate extracted | NR | No studies |
Chronic neck pain and CGH Intermediate‐term High dose of manipulation vs low dose of manipulation | no estimate extracted | 2 studies · 50 participants | Moderate Downgraded: imprecision |
FUNCTION High dose of manipulation vs low dose of manipulation | no estimate extracted | NR | No studies |
aImprecision: ‐1. High dose of manipulation vs low dose of manipulation | no estimate extracted | 1 participants | Ungraded |