Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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Older age vs Younger adults (population mean age <=33.4 years)

Oral health-related quality of life · Adolescents (10-19 years)

The abstract reports older age is associated with worse OHRQoL, but the body notes the evidence on age is limited and conflicting (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Operative treatment of dental caries lesions vs No caries treatment

Oral health-related quality of life · Adolescents (10-19 years)

Operative treatment of caries lesions has a positive effect on OHRQoL in adolescents, though the included evidence was of low quality (narrative synthesis; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    the operative treatment of caries lesions has a positive effect on OHRQoL, despite the low quality of evidence [9]. There is low evidence that the OHRQoL of children and adolescents improved following caries…
    Studies not reported
    GRADE not reported

Periodontal disease assessed by loss of attachment (LOA / clinical attachment loss) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

No difference in OHRQoL was seen between groups for periodontal disease by LOA on OHIP-14/OIDP (pooled SMD -0.04, CI includes 0); ungraded.

3 findings from 1 review

Periodontal disease (severe periodontitis) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Adolescents (10-19 years)

Severe periodontal disease is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review

Periodontal disease assessed by Community Periodontal Index (CPI) vs Individuals without periodontal disease (by CPI)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

Evidence on periodontal disease (CPI) and OHRQoL is inconsistent across studies (very low certainty).

3 findings from 1 review

Gingivitis (assessed by gingival index or WHO criteria) vs Individuals without gingivitis

Oral health-related quality of life · Indians

Continuous analyses (GOHAI, OHIP-14) of gingivitis and OHRQoL were inconsistent and mostly non-significant; ungraded.

2 findings from 1 review

Dental caries vs Absence/lower severity of dental caries

Oral health-related quality of life · Adolescents (10-19 years)

Dental caries is associated with worse OHRQoL in adolescents, with greater severity linked to greater impact (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The impact of dental caries on OHRQoL was addressed in five systematic reviews [9, 26, 34, 36, 37]. Three articles report that the greater the severity of the carious lesion, the worse the impact on OHRQoL in…
    5 studies
    GRADE not reported

Female sex vs Male sex

Oral health-related quality of life · Adolescents (10-19 years)

The abstract reports female sex is associated with worse OHRQoL, but the conclusion states the impact of gender was not clarified (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Dental caries vs Caries-free controls

Oral health-related quality of life · Indian children aged 3-5 years

In children aged 3-5 years, early childhood caries was significantly associated with poorer OHRQoL (narrative; 3 studies); ungraded.

1 finding from 1 review

Higher family income / socioeconomic status vs Lower income / worse socioeconomic status

Oral health-related quality of life · Adolescents (10-19 years)

Higher family income / better socioeconomic status is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Worse oral health status, older age, female sex and worse socioeconomic status were significantly…
    Studies not reported
    GRADE not reported

Completed orthodontic treatment vs Untreated / never received orthodontic treatment

Oral health-related quality of life · Adolescents (10-19 years)

Completing orthodontic treatment is associated with improved OHRQoL in adolescents (narrative synthesis; included reviews report low-to-moderate certainty; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents who had never received orthodontic treatment had a greater impact on quality of life compared to patients who had already completed treatment [34, 40, 44-46]. Orthodontic treatment during childhood or…
    Studies not reported
    GRADE not reported

Prosthetic need vs Individuals without prosthetic need

Oral health-related quality of life · Indian elderly and general-population adults

Prosthetic need was significantly associated with poorer OHRQoL in both included studies (moderate certainty).

3 findings from 1 review

Missing teeth / tooth loss vs No tooth loss

Oral health-related quality of life · Adolescents (10-19 years)

Tooth loss/edentulism is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review

Bruxism vs No bruxism

Oral health-related quality of life · Adolescents (10-19 years)

Bruxism was not shown to impact OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Dental erosion vs No dental erosion

Oral health-related quality of life · Adolescents (10-19 years)

The umbrella review reported that dental erosion has not been shown to affect oral health-related quality of life.

2 findings from 1 review

Dental fluorosis (assessed by TFI or WHO criteria) vs Individuals without dental fluorosis

Oral health-related quality of life · Indian children and young adults

Two studies found dental fluorosis significantly associated with poorer OHRQoL; narrative, ungraded.

1 finding from 1 review