Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,126 questions · 1,225 findings · 111 reviews

No studies found 235 · 19.2%GRADE not reported 260 · 21.2%Very low 207 · 16.9%Low 271 · 22.1%Moderate 177 · 14.4%High 75 · 6.1%

Low molecular weight heparin vs vitamin K antagonist (VKA)

Recurrent VTE · patients with symptomatic VTE requiring long term treatment (3 months) for symptomatic VTE

LMWH showed no clear difference in incidence of recurrent VTE (treatment duration 3 months) compared with VKA (moderate certainty).

1 finding from 1 review

Low molecular weight heparin vs vitamin K antagonist (VKA)

Major bleeding · patients with symptomatic VTE requiring long term treatment (3 months) for symptomatic VTE

LMWH may leads to lower incidence of major bleeding (treatment duration 3 months) compared with VKA (low certainty).

1 finding from 1 review

Low molecular weight heparin vs vitamin K antagonist (VKA)

Mortality (treatment duration 3 months) · patients with symptomatic VTE requiring long term treatment (3 months) for symptomatic VTE

LMWH showed no clear difference in mortality (treatment duration 3 months) compared with VKA (moderate certainty).

1 finding from 1 review

Intervention not reported

HIV infection status of the child · HIV‐positive women during pregnancy and immediate postpartum period

The intervention showed no clear difference in HIV infection status of the child (moderate certainty).

1 finding from 1 review

Intervention not reported

Mean birthweight · HIV‐positive women during pregnancy and immediate postpartum period

The intervention showed no clear difference in mean birthweight (low certainty).

1 finding from 1 review

Intervention not reported

Low birthweight · HIV‐positive women during pregnancy and immediate postpartum period

The intervention probably leads to lower low birthweight (moderate certainty).

1 finding from 1 review

Intervention not reported

Child death by two years of age · HIV‐positive women during pregnancy and immediate postpartum period

The intervention showed no clear difference in child death by two years of age (low certainty).

1 finding from 1 review

Intervention not reported

Preterm delivery · HIV‐positive women during pregnancy and immediate postpartum period

It is very uncertain whether the intervention changes preterm delivery (very low certainty).

1 finding from 1 review

Intervention not reported

Stillbirth · HIV‐positive women during pregnancy and immediate postpartum period

It is very uncertain whether the intervention changes stillbirth (very low certainty).

1 finding from 1 review

Intervention not reported

Maternal death · HIV‐positive women during pregnancy and immediate postpartum period

It is very uncertain whether the intervention changes maternal death (very low certainty).

1 finding from 1 review