Findings

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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS vs STANDARD DOSE ANTIPSYCHOTICS

Mental state: PANSS (not improved, reduced rated < 25%, short‐term) · patients with schizophrenia

It is very uncertain whether ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS changes mental state: PANSS (not improved, reduced rated < 25%, short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

ACUPUNCTURE added to TCM DRUG vs TCM DRUG

Global state: no improvement ‐ medium termAs defined in each study · patients with schizophrenia

ACUPUNCTURE added to TCM DRUG may leads to lower global state: Not improved (talk, behaviour and expression still… compared with TCM DRUG (low certainty).

1 finding from 1 review

Acupuncture vs TCM DRUG

Global state: not improved ‐ short‐term GAF · patients with schizophrenia

ACUPUNCTURE may leads to lower global state: Not improved, endpoint (short‐term) ‐ Not improved (no… compared with TCM DRUG (low certainty).

1 finding from 1 review

ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS vs STANDARD DOSE ANTIPSYCHOTICS

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

It is very uncertain whether ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS changes behaviour: Leaving the study early (short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Acupuncture vs TCM DRUG

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia
1 finding from 1 review

ELECTRIC ACUPUNCTURE CONVULSIVE THERAPY vs ECT

Adverse effects: Spinal fracture (short‐term) · patients with schizophrenia

ELECTRIC ACUPUNCTURE CONVULSIVE THERAPY may leads to lower adverse effects: Spinal fracture (short‐term) compared with ELECTROCONVULSIVE THERAPY (low certainty).

1 finding from 1 review

ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS vs STANDARD DOSE ANTIPSYCHOTICS

Adverse effects: Central Nervous System ‐ insomnia (short‐term) · patients with schizophrenia

ACUPUNCTURE added to STANDARD DOSE ANTIPSYCHOTICS may leads to lower adverse effects: Central Nervous System ‐ insomnia (short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (low certainty).

1 finding from 1 review

ACUPUNCTURE added to LOW DOSE ANTIPSYCHOTICS vs STANDARD DOSE ANTIPSYCHOTICS

Mental state: 2. Not improved (BPRS, < 30% decrease in BPRS score) · patients with schizophrenia

It is very uncertain whether ACUPUNCTURE added to LOW DOSE ANTIPSYCHOTICS changes mental state: BPRS (not improved, reduced rate < 30%, short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Loratadine 10 mg vs hydroxyzine 25 mg

Complete suppression of urticaria: short‐term duration of intervention Global assessment of symptom scores · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in complete suppression of urticaria: short‐term duration of… compared with hydroxyzine 25 mg (low certainty).

1 finding from 1 review

SULPIRIDE vs placebo

Mental state: 2. Specific‐ Positive symptoms, total score‐ average endpoint scores (SADS‐C‐PD scale, lower = better) · patients with schizophrenia
1 finding from 1 review

SULPIRIDE vs placebo

Mental state: average score for negative symptoms ‐ by short term Manchester Scale, negative subset endpoint. Scale from: 0 to 20. · patients with schizophrenia
1 finding from 1 review