Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Exercise vs no treatment

Intensity of disease signs and symptoms1 · people with non‐ulcerated chronic venous insufficiency

It is very uncertain whether physical exercise changes intensity of disease signs and symptoms: VCSS Scale: 0 to 30 (lower… compared with no treatment (very low certainty).

1 finding from 1 review

Triple therapy vs LABA/LAMA combination

Respiratory HRQoL measured by SGRQ, ≥ 4‐point decrease from baseline (lower scores indicate better HRQoL) · stable COPD

Triple therapy leads to higher respiratory HRQoL measured by SGRQ, ≥ 4‐point decrease from baseline… compared with LABA/LAMA combination (high certainty).

1 finding from 1 review

Dextrose gel vs placebo

Major neurological disability at 2 years of age (Defined as any of the following: legal blindness, sensorineural deafness requiring hearing aids, moderate or severe cerebral palsy or developmental delay/intellectual impairment (developmental quoti... · newborn infants at risk of neonatal hypoglycaemia

Dextrose gel showed no clear difference in major neurological disability at 2 years of age (Defined as any of… compared with placebo (low certainty).

1 finding from 1 review

Peritoneoscopic vs open surgical PD catheter insertion

Long‐term PD catheter function (> 4 weeks following PD catheter insertion) · improving catheter function and clinical outcomes in PD patients

It is very uncertain whether peritoneoscopic changes long‐term PD catheter function (> 4 weeks following PD catheter… compared with open surgical PD catheter insertion (very low certainty).

1 finding from 1 review

Medical vs open surgical PD catheter insertion

Late PD catheter failure (> 4 weeks following PD catheter insertion) · improving catheter function and clinical outcomes in PD patients

It is very uncertain whether medical changes late PD catheter failure (> 4 weeks following PD catheter insertion) compared with open surgical PD catheter insertion (very low certainty).

1 finding from 1 review

Intervention not reported

Quality of care: proportion of patients who receive a swallow screen within 24 hours of admission · health professionals providing care to patients with stroke

The intervention probably leads to higher quality of care: proportion of patients who receive a swallow screen… (moderate certainty).

1 finding from 1 review