Cochrane · systematic review · CD013085
Balneotherapy for chronic venous insufficiency
de Moraes Silva, MA, Nakano, LCU, Cisneros, LL, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
11
No studies
10
Included studies
NR
No studies 10 · 47.6%Ungraded 0 · 0%Very low 6 · 28.6%Low 4 · 19%Moderate 1 · 4.8%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsBalneotherapy compared to no treatment for chronic venous insufficiency
Population: people with chronic venous insufficiency
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Disease severity signs and symptoms score (VCSS, scale 0–27, lower is better) Balneotherapy vs no treatment | no estimate extracted | 3 studies · 671 participants | Moderate Downgraded: risk of bias, inconsistency |
Health‐related quality of life(CIVIQ2, scale 20–100, lower is better) Balneotherapy vs no treatment | no estimate extracted | 2 studies · 153 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects of treatment (thromboembolic event) Balneotherapy vs no treatment | OR 0.35 [0.09, 1.42] | 3 studies · 584 participants | Low Downgraded: risk of bias, imprecision |
Pain (VAS, scale 0–10, lower is better) Balneotherapy vs no treatment | no estimate extracted | 2 studies · 354 participants | Low Downgraded: risk of bias |
Oedema(leg circumference in cm, lower is better) Balneotherapy vs no treatment | no estimate extracted | 3 studies · 369 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Incidence of leg ulcer Balneotherapy vs no treatment | OR 1.06 [0.27, 4.14] | 2 studies · 449 participants | Very low Downgraded: risk of bias, imprecision |
Skin pigmentation changes (pigmentation index, 0–10, lower is better) Balneotherapy vs no treatment | no estimate extracted | 1 study · 59 participants | Low Downgraded: risk of bias, imprecision |
Balneotherapy compared to melilotus officinalis for chronic venous insufficiency
Population: people with chronic venous insufficiency
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Disease severity signs and symptoms score Balneotherapy vs melilotus officinalis | no estimate extracted | NR | No studies |
Health‐related quality of life Balneotherapy vs melilotus officinalis | no estimate extracted | NR | No studies |
Adverse effects of treatment Balneotherapy vs melilotus officinalis | no estimate extracted | NR | No studies |
Pain (% of participants) Balneotherapy vs melilotus officinalis | OR 0.29 [0.03, 2.87] | 1 study · 35 participants | Very low Downgraded: risk of bias, imprecision |
Oedema (% of participants) Balneotherapy vs melilotus officinalis | OR 0.21 [0.02, 2.27] | 1 study · 35 participants | Very low Downgraded: risk of bias, imprecision |
Incidence of leg ulcer Balneotherapy vs melilotus officinalis | no estimate extracted | NR | No studies |
Skin pigmentation changes Balneotherapy vs melilotus officinalis | no estimate extracted | NR | No studies |
Balneotherapy compared to dryland exercise for chronic venous insufficiency
Population: people with chronic venous insufficiency
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Disease severity signs and symptoms score Balneotherapy vs dryland exercise | no estimate extracted | NR | No studies |
Health‐related quality of life Balneotherapy vs dryland exercise | no estimate extracted | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Adverse effects of treatment Balneotherapy vs dryland exercise | no estimate extracted | NR | No studies |
Pain Balneotherapy vs dryland exercise | no estimate extracted | NR | No studies |
Oedema (leg volume in mL, lower is better) Balneotherapy vs dryland exercise | no estimate extracted | 1 study · 34 participants | Low Downgraded: risk of bias, imprecision |
Incidence of leg ulcer Balneotherapy vs dryland exercise | no estimate extracted | NR | No studies |
Skin pigmentation changes Balneotherapy vs dryland exercise | no estimate extracted | NR | No studies |