Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

Summary of findings table for oral immunoglobulin vs control

Definite necrotizing enterocolitis (NEC) during study period · preventing necrotizing enterocolitis in preterm and low birth weight neonates

Summary of findings table for oral immunoglobulin showed no clear difference in definite necrotizing enterocolitis (NEC) during study period compared with control (low certainty).

1 finding from 1 review

Summary of findings table for oral immunoglobulin vs control

Definite necrotizing enterocolitis (NEC) during study period ‐ IgA/IgG · preventing necrotizing enterocolitis in preterm and low birth weight neonates

It is very uncertain whether summary of findings table for oral immunoglobulin changes definite necrotizing enterocolitis (NEC) during study period ‐ IgA/IgG compared with control (very low certainty).

1 finding from 1 review

Summary of findings table for oral immunoglobulin vs control

Definite necrotizing enterocolitis (NEC) during study period ‐ IgG · preventing necrotizing enterocolitis in preterm and low birth weight neonates

Summary of findings table for oral immunoglobulin showed no clear difference in definite necrotizing enterocolitis (NEC) during study period ‐ IgG compared with control (low certainty).

1 finding from 1 review

Summary of findings table for oral immunoglobulin vs control

Definite NEC after study period · preventing necrotizing enterocolitis in preterm and low birth weight neonates

It is very uncertain whether summary of findings table for oral immunoglobulin changes definite NEC after study period compared with control (very low certainty).

1 finding from 1 review

Summary of findings table for oral immunoglobulin vs control

NEC‐related surgery during study period · preventing necrotizing enterocolitis in preterm and low birth weight neonates

It is very uncertain whether summary of findings table for oral immunoglobulin changes NEC‐related surgery during study period compared with control (very low certainty).

1 finding from 1 review

Summary of findings table for oral immunoglobulin vs control

NEC‐related deaths during study period · preventing necrotizing enterocolitis in preterm and low birth weight neonates

It is very uncertain whether summary of findings table for oral immunoglobulin changes NEC‐related deaths during study period compared with control (very low certainty).

1 finding from 1 review

Postdischarge formula vs standard term formula

Weight (kg) · preterm infants after hospital discharge
2 findings from 1 review

Postdischarge formula vs standard term formula

Crown‐heel length (mm) · preterm infants after hospital discharge
2 findings from 1 review

Postdischarge formula vs standard term formula

Head circumference (mm) · preterm infants after hospital discharge
2 findings from 1 review