Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,097 questions · 1,119 findings · 70 reviews · Kidney and Transplant

No studies found 271 · 24.2%GRADE not reported 17 · 1.5%Very low 271 · 24.2%Low 349 · 31.2%Moderate 182 · 16.3%High 29 · 2.6%

Scheduled surveillance vs clinical monitoring alone

Risk of access loss · people receiving haemodialysis to treat kidney failure and using a functioning AV access for haemodialysis.

Scheduled surveillance showed no clear difference in risk of access loss compared with clinical monitoring alone (moderate certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Acute rejection, steroid resistant/antibody treated As reported in the articles · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) leads to lower acute rejection, steroid resistant/antibody treated As reported in… compared with azathioprine (AZA) (high certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Infection, CMV tissue invasive As reported in the articles · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) leads to higher infection, CMV tissue invasive As reported in the articles compared with azathioprine (AZA) (high certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Acute rejection, total Any treated acute rejection, including biopsy‐proven · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) leads to lower acute rejection, total Any treated acute rejection, including… compared with azathioprine (AZA) (high certainty).

1 finding from 1 review

Mycophenolate mofetil vs azathioprine (AZA)

Chronic allograft nephropathy Biopsy required in 2 RCTs, one study with optional biopsy · patients with kidney transplant recipients

Mycophenolate mofetil (MMF) may leads to lower chronic allograft nephropathy Biopsy required in 2 RCTs, one study… compared with azathioprine (AZA) (low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in adults and children in patients with and without recurrent UTI Probiotics versus placebo ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in adults and children in patients with… (low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in adults and children with recurrent UTI Probiotics versus placebo ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in adults and children with recurrent UTI… (low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in women with recent UTI Probiotics versus antibiotics ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in women with recent UTI Probiotics versus… (low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic bacterial UTI in children with VUR Probiotics versus placebo ( · adults and children at risk of UTI

The intervention showed no clear difference in symptomatic bacterial UTI in children with VUR Probiotics versus… (low certainty).

1 finding from 1 review