Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye
It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with cyclosporine A (very low certainty).
1 finding from 1 review
Change in fluorescein corneal staining scores (lower is favored) · people with dry eye
Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with lubricants (moderate certainty).
1 finding from 1 review
Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye
It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with lubricants (very low certainty).
1 finding from 1 review
Change in patient‐reported symptom scores (lower is favored) · people with dry eye
Steroids showed no clear difference in change in patient‐reported symptom scores (lower is favored) compared with cyclosporine A (low certainty).
1 finding from 1 review
Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in psychological distress at follow-up compared with usual care, waiting list or no treatment (control) (low certainty).
1 finding from 1 review
Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) may leads to lower pain intensity at follow-up (6-12 months) compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
1 finding from 1 review
Disability caused by pain at follow-up · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in pain disability at follow-up compared with usual care, waiting list or no treatment (control) (low certainty).
1 finding from 1 review
Intervention not reported
Water samples with fluoride concentration below the acceptable range
1 finding from 1 review
Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Lacebacks with fixed appliances showed no clear difference in size of the lower jaw (arch length) compared with fixed appliances only (control); GRADE not reported.
1 finding from 1 review
Size of the lower jaw (arch length, change) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Schwarz appliance showed no clear difference in size of the lower jaw (mandibular arch length, change) at 9 months compared with no active treatment (control); GRADE not reported.
1 finding from 1 review
Water samples with fluoride concentration below the acceptable range · Brazilian cities in the Southeast region with artificially fluoridated public water supplies
In the Southeast region, 24.6% of samples were below the acceptable range.
1 finding from 1 review
Prevalence 24.6
Studies not reported
GRADE not reported
Water samples with fluoride concentration below the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control)
In the Northeast Brazilian region, a pooled 79.7% of water samples had fluoride below the acceptable range; ungraded.
2 findings from 1 review
Amount of crowding (lower incisor crowding) at 10 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether cervical pull headgear changes amount of crowding (lower incisor crowding) at 2 years compared with minor interceptive procedures (control) (very low certainty).
1 finding from 1 review
Endothelial function (flow-mediated dilation) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to higher endothelial function (flow-mediated dilation) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Intervention not reported
Water samples with fluoride concentration below the acceptable range
1 finding from 1 review
Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether schwarz appliance changes amount of crowding (lower arch crowding, change) at 9 months compared with no active treatment (control) (very low certainty).
1 finding from 1 review
Lower incisor inclination (lingual tipping and retrusion) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Self-ligating brackets showed no clear difference in lower incisors to mandible (inclination, degrees) compared with conventional brackets; GRADE not reported.
1 finding from 1 review
Overall survival, post-surgery chemotherapy vs surgery alone (no radiotherapy) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
Surgery +/- radiotherapy + (adjuvant) chemotherapy showed no clear difference in overall survival, adjuvant chemotherapy vs observation alone… compared with surgery +/- radiotherapy alone (observation or adjuvant radiotherapy… (moderate certainty).
1 finding from 1 review
Low birthweight · Pregnant women (healthy and probable zinc deficiency)
Zinc supplementation showed no clear difference in low Birthweight (< 2500 g) compared with no zinc (with or without placebo) (moderate certainty).
1 finding from 1 review
Costs of postnatal care following discharge from hospital in the period up to 6 weeks after the birth · healthy mothers and term infants
1 finding from 1 review